Autoimmune hepatitis (AIH) is increasingly affecting human health but pharmacotherapies
remain to be identified. Growing evidence reveals that ferroptosis, a newly recognized form …

Autoimmune hepatitis (AIH) is an inflammatory autoimmune disease of the liver. Oxidative
stress triggered by reactive oxygen radicals is a common pathophysiological basis for the …

Liver fibrosis, which is characterized by the excessive deposition of extracellular matrix
(ECM) materials (primarily fibrillar collagen-I), is an abnormal repair reaction and …

Nonviral liver disease is a global public health problem due to its high mortality and
morbidity. However, its underlying mechanism is unclear. Ferroptosis is a novel form of cell …

Ferroptosis is a recently recognized form of regulated cell death that is characterized by lipid
peroxidation. However, the molecular mechanisms of ferroptosis in acute immune hepatitis …

Ferroptosis plays a role in several diseases such as iron overload-induced liver diseases.
Manipulation of ferroptosis has been explored as a potential therapeutic strategy to treat …

Fibrosis is a common pathological process that must take place for multiple chronic liver
diseases to develop into cirrhosis and liver cancer. Liver fibrosis (LF) is regulated by various …

Characterized by excessive iron accumulation and lipid peroxidation, ferroptosis is a novel
form of iron-dependent cell death, which is morphologically, genetically, and biochemically …

Ferroptosis is a novel form of cell death, manifested by iron-dependent, non-apoptotic
manner resulting from the intracellular accumulation of large clusters of reactive oxygen …

Ferroptosis is an iron-dependently nonapoptotic cell death characterized by excessive
accumulation of lipid peroxides and cellular iron metabolism disturbances. Impaired iron …