The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons
SA Mahoney, R Hosking, S Farrant… - Journal of …, 2003 - Soc Neuroscience
Expression of the neuropeptide galanin is markedly upregulated within the adult dorsal root
ganglion (DRG) after peripheral nerve injury. We demonstrated previously that the rate of …
ganglion (DRG) after peripheral nerve injury. We demonstrated previously that the rate of …
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain‐like behaviour
SA Hobson, FE Holmes, NCH Kerr… - Journal of …, 2006 - Wiley Online Library
Expression of the neuropeptide galanin is markedly up‐regulated within the adult dorsal root
ganglia (DRG) following peripheral nerve injury. We have previously demonstrated that …
ganglia (DRG) following peripheral nerve injury. We have previously demonstrated that …
Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity
FE Holmes, S Mahoney, VR King… - Proceedings of the …, 2000 - National Acad Sciences
The neuropeptide galanin is expressed developmentally in the dorsal root ganglion (DRG)
and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. Here we …
and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. Here we …
Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTP ases and activation of cofilin
SA Hobson, PA Vanderplank, RJP Pope… - Journal of …, 2013 - Wiley Online Library
We and others have previously shown that the neuropeptide galanin modulates neurite
outgrowth from adult sensory neurons via activation of the second galanin receptor; …
outgrowth from adult sensory neurons via activation of the second galanin receptor; …
Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour
TJS Shi, X Hua, X Lu, S Malkmus… - European Journal of …, 2006 - Wiley Online Library
Galanin is a 29‐amino‐acid peptide expressed in dorsal root ganglion (DRG) neurones and
spinal dorsal horn neurones. It affects pain threshold and has developmental and trophic …
spinal dorsal horn neurones. It affects pain threshold and has developmental and trophic …
Expression and regulation of galanin-R2 receptors in rat primary sensory neurons: effect of axotomy and inflammation
Using in situ hybridization, we studied galanin-R2 receptor (GAL-R2-R) mRNA in rat lumbar
5 dorsal root ganglia (DRGs) at different time points after peripheral tissue inflammation and …
5 dorsal root ganglia (DRGs) at different time points after peripheral tissue inflammation and …
Inducible galanin and GalR2 receptor system in motor neuron injury and regeneration
TCD Burazin, AL Gundlach - Journal of neurochemistry, 1998 - Wiley Online Library
Galanin has been ascribed several physiological roles that are thought to be mediated via
multiple galanin receptors. Recently, two galanin receptors—galanin receptor‐1 (GalR1) …
multiple galanin receptors. Recently, two galanin receptors—galanin receptor‐1 (GalR1) …
Generation and phenotypic characterization of a galanin overexpressing mouse
K Holmberg, E Kuteeva, P Brumovsky, U Kahl… - Neuroscience, 2005 - Elsevier
In most parts of the peripheral nervous system galanin is expressed at very low levels. To
further understand the functional role of galanin, a mouse overexpressing galanin under the …
further understand the functional role of galanin, a mouse overexpressing galanin under the …
Galanin–25 years with a multitalented neuropeptide: galanin acts as a trophic factor to the central and peripheral nervous systems
SA Hobson, A Bacon, CR Elliot-Hunt… - Cellular and Molecular …, 2008 - Springer
The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous
system. Its expression is markedly upregulated in many neuronal tissues after nerve injury or …
system. Its expression is markedly upregulated in many neuronal tissues after nerve injury or …
Galanin acts as a trophic factor to the central and peripheral nervous systems
SA Hobson, A Bacon, CR Elliot-Hunt, FE Holmes… - Galanin, 2010 - Springer
The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous
system. Its expression is markedly up-regulated in many neuronal tissues after nerve injury …
system. Its expression is markedly up-regulated in many neuronal tissues after nerve injury …
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