Disturbed lipid profile in common variable immunodeficiency–a pathogenic loop of inflammation and metabolic disturbances

SF Jorgensen, ME Macpherson… - Frontiers in …, 2023 - frontiersin.org
The relationship between metabolic and inflammatory pathways play a pathogenic role in
various cardiometabolic disorders and is potentially also involved in the pathogenesis of …

Increased plasma levels of triglyceride-enriched lipoproteins associate with systemic inflammation, lipopolysaccharides, and gut dysbiosis in common variable …

ME Macpherson, T Skarpengland, JR Hov… - Journal of Clinical …, 2023 - Springer
Purpose Triglycerides (TG) and their major transport lipoprotein in the circulation (VLDL)
appear to be related to inflammation. Patients with common variable immunodeficiency …

Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency

ME Macpherson, B Halvorsen, A Yndestad… - Scientific Reports, 2019 - nature.com
Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency, characterized by inadequate antibody responses and recurrent bacterial …

[HTML][HTML] Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation

SF Jørgensen, M Trøseid, M Kummen… - Mucosal …, 2016 - Elsevier
Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency characterized by low immunoglobulin (Ig) G and IgA, and/or IgM. In …

Gut microbiome and common variable immunodeficiency: few certainties and many outstanding questions

G Varricchi, R Poto, G Ianiro, A Punziano… - Frontiers in …, 2021 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common symptomatic primary
antibody immunodeficiency, characterized by reduced serum levels of IgG, IgA, and/or IgM …

Dysimmunity in common variable immunodeficiency is associated with alterations in oral, respiratory, and intestinal microbiota

MD Cabanero-Navalon, V Garcia-Bustos, A Mira… - Clinical …, 2023 - Elsevier
Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency characterized by decreased immunoglobulins and recurrent infections. Its …

Bacterial but not fungal gut microbiota alterations are associated with common variable immunodeficiency (CVID) phenotype

K Fiedorová, M Radvanský, J Bosák… - Frontiers in …, 2019 - frontiersin.org
Common Variable Immunodeficiency (CVID) is the most frequent symptomatic immune
disorder characterized by reduced serum immunoglobulins. Patients often suffer from …

Altered plasma fatty acids associate with gut microbial composition in common variable immunodeficiency

T Skarpengland, ME Macpherson, JR Hov… - Journal of Clinical …, 2022 - Springer
Purpose Fatty acid (FA) abnormalities are found in various inflammatory disorders and have
been related to disturbed gut microbiota. Patients with common variable immunodeficiency …

Autoimmunity and inflammation in CVID: a possible crosstalk between immune activation, gut microbiota, and epigenetic modifications

SF Jørgensen, B Fevang, P Aukrust - Journal of clinical immunology, 2019 - Springer
Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency among adults and is characterized by a B cell dysfunction and increased …

Common variable immunodeficiency: crossroads between infections, inflammation and autoimmunity

S Baldovino, D Montin, S Martino, S Sciascia… - Autoimmunity …, 2013 - Elsevier
Common variable immunodeficiency is a collection of diseases characterized by primary
hypogammaglobulinemia. The causes of CVID are extremely heterogeneous and may affect …