[HTML][HTML] Autophagy in human T-cell leukemia virus type 1 (HTLV-1) induced leukemia

N Ducasa, D Grasso, P Benencio… - Frontiers in …, 2021 - frontiersin.org
Viruses play an important role in the development of certain human cancers. They are
estimated to contribute 16% to all human cancers. Human T-cell leukemia virus type 1 …

The cellular autophagy pathway modulates human T-cell leukemia virus type 1 replication

SW Tang, CY Chen, Z Klase, L Zane… - Journal of virology, 2013 - Am Soc Microbiol
Autophagy, a general homeostatic process for degradation of cytosolic proteins or
organelles, has been reported to modulate the replication of many viruses. The role of …

[HTML][HTML] HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagy

T Ren, W Dong, Y Takahashi, D Xiang, Y Yuan… - Journal of Biological …, 2012 - ASBMB
Human T cell leukemia virus type 1 and type 2 (HTLV-1 and-2) are two closely related
retroviruses with the former causing adult T cell leukemia. HTLV-2 infection is prevalent …

HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains

T Ren, Y Takahashi, X Liu, TP Loughran, SC Sun… - Oncogene, 2015 - nature.com
The retroviral oncoprotein Tax from human T-cell leukemia virus type 1 (HTLV-1), an
etiological factor that causes adult T-cell leukemia and lymphoma, has a crucial role in …

Bcl-3, induced by Tax and HTLV-1, inhibits NF-κB activation and promotes autophagy

J Wang, Z Niu, Y Shi, C Gao, X Wang, J Han, J Li… - Cellular signalling, 2013 - Elsevier
The human T cell leukemia virus type 1 (HTLV-1) is a complex human retrovirus that causes
an aggressive leukemia known as adult T cell leukemia (ATL). The HTLV-1-encoded …

Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis

W Wang, J Zhou, J Shi, Y Zhang, S Liu, Y Liu… - Journal of …, 2014 - Am Soc Microbiol
The human T-cell leukemia virus type 1 (HTLV-1) Tax protein is considered to play a central
role in the process that leads to adult T-cell leukemia/lymphoma (ATL) and HTLV-1 …

[HTML][HTML] HTLV-1's Foxy strategy for survival and transmission

Y Higuchi, J Yasunaga, M Matsuoka - Frontiers in Virology, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia-
lymphoma (ATL) and inflammatory diseases including HTLV-1-associated myelopathy …

[HTML][HTML] HTLV-1-mediated epigenetic pathway to adult T-cell leukemia–lymphoma

M Yamagishi, D Fujikawa, T Watanabe… - Frontiers in …, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1), the first reported human oncogenic retrovirus,
is the etiologic agent of highly aggressive, currently incurable diseases such as adult T-cell …

[HTML][HTML] Highlights on distinctive structural and functional properties of HTLV Tax proteins

MG Romanelli, E Diani, E Bergamo, C Casoli… - Frontiers in …, 2013 - frontiersin.org
Human T cell leukemia viruses (HTLVs) are complex human retroviruses of the
Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 …

[HTML][HTML] Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein

M Turci, J Lodewick, G Di Gennaro, AS Rinaldi… - Retrovirology, 2012 - Springer
Abstract Background Retroviruses HTLV-1 and HTLV-2 have homologous genomic
structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell …