Coma is a medical and socioeconomic emergency. Although underfunded, research on
coma and disorders of consciousness has made impressive progress. Lesion-network …

The past 15years have provided an unprecedented collection of discoveries that bear upon
our scientific understanding of recovery of consciousness in the human brain following …

Medicine has been concerned with coma since ancient times. The writings of Hippocrates
reference koma, which is Greek for “deep sleep,” and numerous medical writings from the …

The article discusses study by Bayne and colleagues on shortcomings of current
classification of disorders of consciousness (DOC). Topics discussed include use of the …

Recovery from coma or disordered consciousness is a central issue in patients with acute
brain injuries such as stroke, trauma, cardiac arrest, and brain infections. Yet, major gaps …

Assessments of consciousness are a critical part of prognostic algorithms for critically ill
patients suffering from severe brain injuries. There have been significant advances in the …

Coma resulting from brain injury or illness usually is a transient state. Within a few weeks,
patients in coma either recover awareness, die, or evolve to an eyes-open state of impaired …

Our understanding of the mechanisms of loss and recovery of consciousness, following
severe brain injury or during anesthesia, is changing rapidly. Recent neuroimaging studies …

Background and purpose Patients with acquired brain injury and acute or prolonged
disorders of consciousness (DoC) are challenging. Evidence to support diagnostic decisions …

Objective: We hypothesize that the major consciousness deficit observed in coma is due to
the breakdown of long-range neuronal communication supported by precuneus and …