Unravelling cortico-hypothalamic pathways regulating unconditioned fear-induced antinociception and defensive behaviours
LL Falconi-Sobrinho, T dos Anjos-Garcia… - …, 2017 - Elsevier
The medial prefrontal cortex can influence unconditioned fear-induced defensive
mechanisms organised by diencephalic neurons that are under tonic GABAergic inhibition …
mechanisms organised by diencephalic neurons that are under tonic GABAergic inhibition …
Decrease in NMDA receptor-signalling activity in the anterior cingulate cortex diminishes defensive behaviour and unconditioned fear-induced antinociception elicited …
LL Falconi-Sobrinho, T dos Anjos-Garcia… - European …, 2017 - Elsevier
Acute γ-aminobutyric acid (GABA) disinhibition in the posterior hypothalamus (PH) elicits
defensive reactions that are considered anxiety-and panic attack-like behaviour, and these …
defensive reactions that are considered anxiety-and panic attack-like behaviour, and these …
Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in …
RL de Freitas, CJ Salgado-Rohner… - International Journal …, 2013 - academic.oup.com
It has been shown that GABAA receptor blockade in the dorsomedial and ventromedial
hypothalamic nuclei (DMH and VMH, respectively) induces elaborated defensive …
hypothalamic nuclei (DMH and VMH, respectively) induces elaborated defensive …
NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced …
The aim of the present study was to investigate the involvement of N-methyl-d-aspartate
(NMDA) and amino-3-hydroxy-5-methyl-isoxazole-4-proprionate (AMPA)/kainate receptors …
(NMDA) and amino-3-hydroxy-5-methyl-isoxazole-4-proprionate (AMPA)/kainate receptors …
[HTML][HTML] GABAA receptor blockade in dorsomedial and ventromedial nuclei of the hypothalamus evokes panic-like elaborated defensive behaviour followed by innate …
RL Freitas, A Uribe-Mariño, MA Castiblanco-Urbina… - Brain research, 2009 - Elsevier
Dysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome
in humans. Furthermore, several studies have implicated the hypothalamus in the …
in humans. Furthermore, several studies have implicated the hypothalamus in the …
Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear …
Decrease of γ-aminobutyric acid (GABA)-mediated neurotransmission in the dorsomedial
hypothalamus (DMH) evokes instinctive fear-like responses. The aim of the present study …
hypothalamus (DMH) evokes instinctive fear-like responses. The aim of the present study …
The anterior cingulate cortex and its interface with the dorsal periaqueductal grey regulating nitric oxide-mediated panic-like behaviour and defensive antinociception
LL Falconi-Sobrinho, T dos Anjos-Garcia, MA Rebelo… - …, 2024 - Elsevier
The anterior cingulate cortex (ACC) Cg1 (24b) area modulates glutamate-mediated
unconditioned fear and antinociception organised by hypothalamus. However, it remains …
unconditioned fear and antinociception organised by hypothalamus. However, it remains …
Nitric oxide-mediated defensive and antinociceptive responses organised at the anterior hypothalamus of mice are modulated by glutamatergic inputs from area 24b …
LL Falconi-Sobrinho… - Journal of …, 2021 - journals.sagepub.com
Background: Previous studies suggested that Cg1 area of the cingulate cortex of rats
controls glutamate-mediated fear-induced defensive behaviour and antinociception …
controls glutamate-mediated fear-induced defensive behaviour and antinociception …
Unravelling the dorsal periaqueductal grey matter NMDA receptors relevance in the nitric oxide-mediated panic‑like behaviour and defensive antinociception …
LL Falconi-Sobrinho, T dos Anjos-Garcia… - …, 2023 - Springer
Rationale Previous studies suggested that the dorsal column of the periaqueductal grey
matter (dPAG) can be a target of neural pathways from hypothalamic nuclei involved in …
matter (dPAG) can be a target of neural pathways from hypothalamic nuclei involved in …
The nitric oxide donor SIN-1-produced panic-like behaviour and fear-induced antinociception are modulated by NMDA receptors in the anterior hypothalamus
LL Falconi-Sobrinho… - Journal of …, 2018 - journals.sagepub.com
Background: An excitatory imbalance in the hypothalamus of rodents caused by local
chemical stimulation elicits fear-related defensive reactions such as escape and freezing. In …
chemical stimulation elicits fear-related defensive reactions such as escape and freezing. In …