[HTML][HTML] Leaky Gut Driven by Dysbiosis Augments Activation and Accumulation of Liver Macrophages via RIP3 Signaling Pathway in Autoimmune Hepatitis

H Zhang, M Liu, W Zhong, Y Zheng, Y Li… - Frontiers in …, 2021 - frontiersin.org
The gut–liver axis has been increasingly recognized as a major autoimmunity modulator.
However, the implications of intestinal barrier in the pathogenesis of autoimmune hepatitis …

A novel synbiotic alleviates autoimmune hepatitis by modulating the gut microbiota-liver axis and inhibiting the hepatic TLR4/NF-κB/NLRP3 signaling pathway

Y Kang, X Kuang, H Yan, P Ren, X Yang, H Liu, Q Liu… - Msystems, 2023 - Am Soc Microbiol
Autoimmune hepatitis (AIH) is a liver disease characterized by chronic liver inflammation.
The intestinal barrier and microbiome play critical roles in AIH progression. AIH treatment …

[HTML][HTML] Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction

H Lin, J Lin, T Pan, T Li, H Jiang, Y Fang, Y Wang… - Cell Death & …, 2023 - nature.com
Autoimmune hepatitis (AIH) is an immune-mediated inflammatory liver disease with unclear
pathogenesis. The gut microbiota and intestinal barrier play an essential role in AIH …

[HTML][HTML] The gut microbiota: a novel player in autoimmune hepatitis

Z Cheng, L Yang, H Chu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disease that is distributed
globally in all ethnicities with increasing prevalence. If untreated, the disease will lead to …

The gut microbiome and autoimmune hepatitis: implications for early diagnostic biomarkers and novel therapies

L Li, Y Kang - Molecular Nutrition & Food Research, 2023 - Wiley Online Library
Autoimmune hepatitis (AIH) is a serious chronic liver disease that may last for decades and
eventually develop into cirrhosis and liver failure. In recent years, people have paid more …

[HTML][HTML] RIP3 blockade prevents immune-mediated hepatitis through a myeloid-derived suppressor cell dependent mechanism

M Liu, H Zhang, L Zhang, X Liu, S Zhou… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Autoimmune hepatitis (AIH) is an immune-mediated chronic inflammatory liver disease, and
its pathogenesis is not fully understood. Our previous study discovered that receptor …

[HTML][HTML] Intestinal homeostasis in autoimmune liver diseases

Q Liu, W He, R Tang, X Ma - Chinese Medical Journal, 2022 - journals.lww.com
Intestinal homeostasis depends on complex interactions between the gut microbiota and
host immune system. Emerging evidence indicates that the intestinal microbiota is a key …

[HTML][HTML] Bifidobacterium animalis ssp. Lactis 420 Mitigates Autoimmune Hepatitis Through Regulating Intestinal Barrier and Liver Immune Cells

H Zhang, M Liu, X Liu, W Zhong, Y Li, Y Ran… - Frontiers in …, 2020 - frontiersin.org
Autoimmune hepatitis (AIH) is an immune-mediated inflammatory liver disease of uncertain
cause. Accumulating evidence shows that gut microbiota and intestinal barrier play …

[HTML][HTML] The gut–liver axis in immune remodeling of hepatic cirrhosis

H Guan, X Zhang, M Kuang, J Yu - Frontiers in Immunology, 2022 - frontiersin.org
In healthy settings, the gut–liver axis allows host–microbiota communications and mediates
immune homeostasis through bidirectional regulation. Meanwhile, in diseases, gut …

[HTML][HTML] The gut-liver axis in immune remodeling: new insight into liver diseases

X Yang, D Lu, J Zhuo, Z Lin, M Yang… - International journal of …, 2020 - ncbi.nlm.nih.gov
The gut microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea,
and protozoans, playing a fundamental role in the induction, training, and function of the …