The process of normal aging affects organ homeostasis as well as responses to acute and
chronic injury. In view of the rapid growth in the elderly population, it is increasingly …

Epidemiologic, clinical, and molecular evidence suggest that aging is a major contributor to
the increasing incidence of acute kidney injury and chronic kidney disease. The aging …

As human life expectancy keeps increasing, ageing populations present a growing
challenge for clinical practices. Human ageing is associated with molecular, structural, and …

Individuals age> 65 years old are the fastest expanding population demographic throughout
the developed world. Consequently, more aged patients than before are receiving …

Pedigree genetics and environment modulate the biological process of aging. The
permanent and irreversible growth arrest of cell senescence is a central paradigm of aging …

The age‐dependent changes in the kidney are often debilitating, can be life‐threatening and
are a significant cause of increasing health costs worldwide. Excessive fibrosis, a general …

Renal aging, by itself, is associated with alterations in renal morphology and a decline in
renal function, which is accelerated and/or accentuated by diseases such as diabetes …

Kidneys are among the organs affected by the aging process. Aging kidneys are
characterized by progressive scarring and measurable declines in renal function …

Three decades have passed since a series of studies indicated that the aging kidney was
characterized by increased susceptibility to nephrotoxic injury. Data from these experimental …

The prevalence of diagnosed CKD is high among individuals older than 65 years. Since
GFR declines with normal aging, this phenomenon is due in part to the use of a single …