[HTML][HTML] In vivo evaluation of the subchronic systemic toxicity of akermanite bioceramic for bone regeneration following ISO standard methods

N Ma, B Ma, Y Zhou, H Zhu, Y Zhou, Z Huan, P Wang… - RSC …, 2019 - pubs.rsc.org
Although the akermanite (Ca2MgSi2O7) bioceramic has been confirmed to possess
favorable osteogenic activity, until now little was known about its in vivo subchronic systemic …

In vitro and in vivo evaluation of akermanite bioceramics for bone regeneration

Y Huang, X Jin, X Zhang, H Sun, J Tu, T Tang, J Chang… - Biomaterials, 2009 - Elsevier
This study investigated the effects of a calcium magnesium silicate bioceramic (akermanite)
for bone regeneration in vitro and in vivo, with β-tricalcium phosphate (β-TCP) as a control …

A novel akermanite bioceramic: preparation and characteristics

C Wu, J Chang - Journal of biomaterials applications, 2006 - journals.sagepub.com
Akermanite (Ca2MgSi2O7) ceramics are prepared by sintering akermanite powder
compacts at 1370 C for 6 h. The sintering behavior and mechanical properties of akermanite …

Recent advances on akermanite calcium‐silicate ceramic for biomedical applications

P Zadehnajar, MH Mirmusavi… - … Journal of Applied …, 2021 - Wiley Online Library
Owing to great biocompatibility and high capacity of apatite formation, bioceramics,
especially calcium silicate‐based compounds, were extensively employed in orthopedic and …

In vitro bioactivity of akermanite ceramics

C Wu, J Chang, S Ni, J Wang - … Part A: An Official Journal of …, 2006 - Wiley Online Library
In this study, the bone‐like apatite‐formation ability of akermanite ceramics (Ca2MgSi2O7)
in simulated body fluid (SBF) and the effects of ionic products from akermanite dissolution on …

Effect of strontium substitution on structural, sinterability, physicomechanical and biological properties of akermanite ceramic

H Mohammadi, YMB Ismail, KA Shariff… - Journal of the Mechanical …, 2021 - Elsevier
Despite the excellent in vitro and in vivo performance of akermanite ceramic, its poor
toughness and strength limit the biomedical application, particularly under load. Herein, the …

Fabrication of akermanite scaffolds with high bioactivity and mechanical properties suitable for bone tissue engineering application

RA Youness, MF Zawrah, MA Taha - Ceramics International, 2024 - Elsevier
This study focuses on the relationship between porosity, surface roughness, microstructure,
strength, and thermal properties, as well as their effect on the bioactivity and …

[HTML][HTML] Assessment of cobalt substitution on the structural, physico-mechanical, and in vitro degradation of akermanite ceramic

H Mohammadi, YMB Ismail, KA Shariff… - Journal of Science …, 2021 - Elsevier
The effects of cobalt (Co) substitution on the structural, physico-mechanical properties, as
well as the in vitro bioactivity and biodegradability of akermanite (Ca 2 MgSi 2 O 7) are …

Synthesis, characterization, and in vitro bioactivity, mechanical strength of silver doped akermanite bioceramic

K Shobana, S Swamiappan - Inorganic Chemistry Communications, 2023 - Elsevier
Biomaterials research has grown in recent decades, due to the necessity of organ, tissue,
and bone repair. The foremost goal of this work is to prepare silver-doped bioceramic in …

[HTML][HTML] Fabrication, mechanical properties and in-vitro behavior of akermanite bioceramic

F Tavangarian, CA Zolko, S Sadeghzade, M Fayed… - Materials, 2020 - mdpi.com
Pure nanocrystalline akermanite (Ca2MgSi2O7) powder was synthesized by mechanical
activation with subsequent annealing of talc, calcium carbonate, and silicate powders as the …