Hemispheric epilepsy surgery for hemimegalencephaly: The UCLA experience

K Goel, HW Phillips, JS Chen, J Ngo, B Edmonds… - …, 2024 - Wiley Online Library
Objectives Hemimegalencephaly (HME) is a rare congenital brain malformation presenting
predominantly with drug‐resistant epilepsy. Hemispheric disconnective surgery is the …

Hemimegalencephaly: A Systematic Comparison of Functional and Anatomic Hemispherectomy for Drug-Resistant Epilepsy

K Goel, A Ghadiyaram, A Krishnakumar… - …, 2024 - journals.lww.com
METHODS: PubMed, Web of Science, and Cumulative Index to Nursing and Allied Health
Literature were searched from inception to Jan 13th, 2023, for primary literature reporting …

Prognostic Value of Preoperative and Postoperative Electroencephalography Findings in Pediatric Patients Undergoing Hemispheric Epilepsy Surgery

PY Ko, D Barry, H Shurtleff, JS Hauptman… - World neurosurgery, 2022 - Elsevier
Objective The seizure outcomes after hemispheric epilepsy surgery have been excellent,
with 54%–90% of patients achieving long-term freedom from seizures. Similarly, the …

Functional cognitive and language outcomes after cerebral hemispherectomy for hemimegalencephaly

K Puka, M Jones, GW Mathern - Epilepsia, 2021 - Wiley Online Library
Objective Hemispheric surgeries are an effective treatment option to control seizures for
children with hemimegalencephaly (HME); however, not enough is known about their …

Hemispherectomy and epileptic encephalopathy

MS Duchowny - Epilepsy Currents, 2004 - journals.sagepub.com
OBJECTIVE: To compare hemispherectomy patients with different pathologic substrates for
hospital course, seizure, developmental, language, and motor outcomes. METHODS: The …

The natural history of postoperative hydrocephalus after pediatric hemispherectomy for medically refractory epilepsy: an institutional experience

VM Lu, S Wang, J Ragheb - Journal of Neurosurgery: Pediatrics, 2023 - thejns.org
OBJECTIVE Hemispherectomy is a complex surgical intervention for medically refractory
epilepsy, and its surgical sequelae continue to be defined. The incidence, timing, and …

Seizure outcome, functional outcome, and quality of life after hemispherectomy in adults

J Schramm, D Delev, J Wagner, CE Elger… - Acta …, 2012 - Springer
Background Functional hemispherectomy is a well-established method in childhood
epilepsy surgery with only a few reports on its application in adults. Methods We report on …

Functional hemispherectomy: can preoperative imaging predict outcome?

AG Weil, A Fallah, S Wang, GM Ibrahim… - Journal of …, 2020 - thejns.org
OBJECTIVE Although hemispherectomy is an effective treatment for children with intractable
hemispheric epilepsy syndromes, as many as 40% of patients eventually develop seizure …

Hemispherotomy in infants with hemimegalencephaly: long-term seizure and developmental outcome in early treated patients

C Pepi, A De Benedictis, MC Rossi-Espagnet… - Brain Sciences, 2022 - mdpi.com
Hemimegalencephaly (HME) is a rare brain congenital malformation, consisting in altered
neuronal migration and proliferation within one hemisphere, which is responsible for early …

Clinical outcomes of pediatric hemispherectomy following unsuccessful subhemispheric resection for refractory epilepsy: a case review study

LF Akiyama, EA Roberts, HA Shurtleff, D Barry… - Journal of …, 2023 - thejns.org
OBJECTIVE Epilepsy surgery remains one of the most underutilized procedures in epilepsy
despite its proven superiority to other available therapies. This underutilization is greater in …