Prospects for mucosal vaccine: shutting the door on SARS-CoV-2

R Mudgal, S Nehul, S Tomar - Human vaccines & …, 2020 - Taylor & Francis
The sudden emergence of a highly transmissible and pathogenic coronavirus SARS-CoV-2
in December 2019 from China and its rapid global spread has posed an international health …

Oral and intranasal vaccines against SARS‐CoV‐2: Current progress, prospects, advantages, and challenges

S Kar, P Devnath, TB Emran, TE Tallei… - Immunity …, 2022 - Wiley Online Library
Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
caused a deadly pandemic in the 21st century, resulting in many deaths, economic loss, and …

[HTML][HTML] Promises and challenges of mucosal COVID-19 vaccines

APS Rathore, ALS John - Vaccine, 2023 - Elsevier
Abstract Coronavirus disease-2019 (COVID-19) is an ongoing pandemic caused by the
newly emerged virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

SARS-CoV-2: immunity, challenges with current vaccines, and a novel perspective on mucosal vaccines

R Sunagar, A Singh, S Kumar - Vaccines, 2023 - mdpi.com
The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …

Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report

JM Knisely, LE Buyon, R Mandt, R Farkas… - npj Vaccines, 2023 - nature.com
On November 7th and 8th, 2022, The National Institute of Allergy and Infectious Diseases
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …

[HTML][HTML] Mucosal COVID-19 vaccines: Risks, benefits and control of the pandemic

D Miteva, M Peshevska-Sekulovska… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Based on mucosal immunization to promote both mucosal and systemic immune responses,
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …

[HTML][HTML] Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines

V Mouro, A Fischer - Mucosal immunology, 2022 - Elsevier
The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …

Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?

L Moreno-Fierros, I García-Silva… - Expert Opinion on …, 2020 - Taylor & Francis
The COVID-19 pandemic caused by the SARS-CoV-2 virus is having an unprecedented
impact on global health derived from its quick spread, which is attributed to its high stability …

Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

S Afkhami, MR D'Agostino, A Zhang, HD Stacey… - Cell, 2022 - cell.com
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current
COVID-19 vaccines administered intramuscularly and designed to only target the spike …

[HTML][HTML] Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques

Y Sui, J Li, R Zhang, SK Prabhu, H Andersen… - JCI insight, 2021 - ncbi.nlm.nih.gov
Effective SARS-CoV-2 vaccines are urgently needed. Although most vaccine strategies have
focused on systemic immunization, here we compared the protective efficacy of 2 …