Profiling bovine blastocyst transcriptome at the single-cell level has enabled us to reveal the
first cell lineage segregation, during which the inner cell mass (ICM), trophectoderm (TE) …

Embryo morphokinetics suggests that the timing of the first embryonic cell divisions may
predict the developmental potential of an embryo; however, correlations between embryonic …

Mice and cattle use distinct pathways for the first cell segregation into inner cell mass (ICM)
and trophectoderm (TE) lineages at the blastocyst stage. However, limited knowledge is …

An understanding of gene expression patterns due to altered environmental conditions
during different time points of the pre-implantation period would improve our knowledge on …

Reproducing the environment to which the embryo is naturally exposed may be an
alternative to improve viability of embryos produced in vitro. In the first part of this work, we …

The time-lapse system is a non-invasive method that enables a continuous evaluation
through embryo development. Here, we examined the association between the …

Background This study describes the generation and analysis of the transcriptional profile of
bovine inner cell mass (ICM) and trophectoderm (TE), obtained from in vivo developed …

Cloning cattle using somatic cell nuclear transfer (SCNT) is inefficient. Although the rate of
development of SCNT embryos in vitro is similar to that of fertilized embryos, most fail to …

Trophectoderm of blastocysts mediate early events in fetal-maternal communication,
enabling implantation and establishment of a functional placenta. Inadequate or impaired …

In vitro embryo culture systems promote development at rates lower than in vivo systems.
The goal of this project was to discover transcripts that may be responsible for a decrease of …