Glutamate has been found to play an unexpectedly important role in neuroendocrine
regulation in the hypothalamus, as revealed in converging experiments with ultrastructural …

The hypothalamus is the crucial part of the brain that regulates homeostasis throughout the
body. It governs the endocrine and autonomic nervous systems, temperature, heart rate …

Light microscopy immunohistochemical techniques were used to examine the distribution of
glutamine synthetase in rat brain. Glutamine synthetase was found to be localized in the …

The microiontophoretic application of thyrotropin-releasing hormone causes a selective
reduction in neuronal excitation evoked by L-glutamate but not by acetylcholine in rat …

Microinjection of L-glutamate into the intermediate nucleus tractus solitarii in anesthetized
rats elicits hypotension, bradycardia, and apnea, simulating baroreceptor reflexes. Ablation …

Although several recent anatomical and physiological studies indicate that glutamate
receptors are likely to play a role in the regulation of various hypothalamic functions, no …

The glutamate receptors mediate excitatory neurotransmission in the brain and are
important in memory acquisition, learning, and some neurodegenerative disorders. This …

In situ hybridization and Northern blots were used to study the ionotropic subtypes of the
glutamate receptor in the rat hypothalamus. Widespread expression of AMPA, kainate, and …

Within the hypothalamus, a large number of neuroactive substances are found, many first
detected in this part of the brain. Excitatory amino acids, recognized as important …

Excitatory amino acids (EAAs), such as glutamate and aspartate, are found in large
concentrations in presynaptic boutons of a variety of important hypothalamic nuclei …