Relating clinical symptoms to neuroanatomical profiles of brain damage and ultimately to
tissue pathology is a key challenge in the field of neurodegenerative disease and …

One year ago, in this journal, we published a recommended nomenclature for the
neuropathologic subtypes of frontotemporal lobar degeneration (FTLD)[7]. A major impetus …

Frontotemporal lobar degeneration (FTLD) encompasses a heterogeneous group of clinical
syndromes that include frontotemporal dementia (FTD), frontotemporal dementia with motor …

The term frontotemporal dementia (FTD) encompasses a range of clinical syndromes that
are believed not to map reliably onto the spectrum of recognized pathologies. This study …

Background: We sought to describe the antemortem clinical and neuroimaging features
among patients with frontotemporal lobar degeneration with TDP-43 immunoreactive …

Neural network breakdown is a key issue in neurodegenerative disease, but the
mechanisms are poorly understood. Here we investigated patterns of brain atrophy …

Objective The pathology of frontotemporal dementia, termed frontotemporal lobar
degeneration (FTLD), is characterized by distinct molecular classes of aggregated proteins …

Antemortem behavioural and anatomic abnormalities have largely been associated with
right hemisphere disease in behavioural-variant frontotemporal dementia, but post-mortem …

Frontotemporal dementia (FTD) phenotypes have distinctive and well-established cortical
signatures, but their subcortical grey matter profiles are poorly characterised. The …

Frontotemporal dementia (FTD) is the second most common young-onset dementia and is
clinically characterised by progressive behavioural change, executive dysfunction and …