FGF10, as an FGFR2b-specific ligand, plays a crucial role during cell proliferation, multi-
organ development, and tissue injury repair. The developmental importance of FGF10 has …

The Fgf family comprises 22 members with diverse functions in development, repair,
metabolism, and neuronal activities. Fgf10 mediates biological responses by activating Fgf …

The FGF family comprises 22 members with diverse functions in development and health.
FGF10 specifically activates FGFR2b in a paracrine manner with heparan sulfate as a co …

Fibroblast growth factors (FGFs) are diffusible polypeptides released by a variety of cell
types. FGF8 subfamily members regulate embryonic development processes through …

Members of the fibroblast growth factor (FGF) family have myriad functions during
development of both non-vertebrate and vertebrate organisms. One of these family …

The Fgf signalling pathway is highly conserved in evolution and plays crucial roles in
development. In the craniofacial region, it is involved in almost all structure development …

FGF receptor 2 isoform IIIb (FGFR2b), originally discovered as a receptor for FGF7, is known
to be an important receptor in vertebrate morphogenesis, because FGFR2b null mice exhibit …

Thirteen affected individuals of six generations of a single kindred presented with epiphora
evident from infancy. Physical exam and Schirmer test revealed variable expression of tear …

Fibroblast Growth Factor 10 (FGF10) is a multifunctional mesenchymal-epithelial signaling
growth factor, which is essential for multi-organ development and tissue homeostasis in …

Mammalian fibroblast growth factor (FGF) signaling is intricately regulated via selective
binding interactions between 18 FGF ligands and four FGF receptors (FGFR1–4), three of …