EAACI Biologicals Guidelines—dupilumab for children and adults with moderate‐to‐severe atopic dermatitis

I Agache, CA Akdis, M Akdis, K Brockow, T Chivato… - Allergy, 2021 - Wiley Online Library
Atopic dermatitis imposes a significant burden on patients, families and healthcare systems.
Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care …

Efficacy and safety of dupilumab for moderate‐to‐severe atopic dermatitis: a systematic review for the EAACI biologicals guidelines

I Agache, Y Song, M Posso, P Alonso‐Coello… - Allergy, 2021 - Wiley Online Library
This systematic review evaluates the efficacy, safety and economic impact of dupilumab
compared to standard of care for uncontrolled moderate‐to‐severe atopic dermatitis (AD) …

Biologics for treatment of atopic dermatitis: current status and future prospect

T Ratchataswan, TM Banzon, JP Thyssen… - The Journal of Allergy …, 2021 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …

Dupilumab in daily practice for the treatment of pediatric atopic dermatitis: 28‐week clinical and biomarker results from the BioDay registry

E Kamphuis, CM Boesjes, L Loman… - Pediatric Allergy and …, 2022 - Wiley Online Library
Background Dupilumab has proven to be an effective and safe treatment for atopic
dermatitis (AD) in pediatric patients in clinical trials. However, few daily practice studies are …

New and emerging targeted systemic therapies: a new era for atopic dermatitis

DE Lee, AK Clark, KA Tran, VY Shi - Journal of Dermatological …, 2018 - Taylor & Francis
Purpose: This is a review of emerging targeted, systemic therapies for atopic dermatitis (AD).
The information presented aims to provide dermatologists with updated therapeutic options …

Dupilumab Treatment in Pediatric Patients Aged 6–11 Years with Severe Atopic Dermatitis Whose Disease Is Not Adequately Controlled: A Review

MJ Cork, SG Danby, AB Rossi… - … Design, Development and …, 2024 - Taylor & Francis
Atopic dermatitis (AD) is the most common inflammatory skin disease in children. Children
with severe AD have a multidimensional disease burden characterized by skin lesions …

Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial

AS Paller, EL Simpson, EC Siegfried, MJ Cork… - The Lancet, 2022 - thelancet.com
Background Current systemic treatments for children younger than 6 years with moderate-to-
severe atopic dermatitis that is uncontrolled with topical therapies might have suboptimal …

Dupilumab for the treatment of adolescents with atopic dermatitis

S Senner, M Seegräber, S Frey… - Expert Review of …, 2020 - Taylor & Francis
Introduction Dupilumab is a treatment option newly licensed for adolescents with moderate
to severe atopic dermatitis (AD). It reduces type 2 inflammation by blocking the shared …

Dupilumab improves clinical scores in children and adolescents with moderate to severe atopic dermatitis: a real-world, single-center study

AD Pagan, E David, B Ungar, S Ghalili, H He… - The Journal of Allergy …, 2022 - Elsevier
Background Dupilumab has proven safe and effective in children and adolescents with
atopic dermatitis (AD) in clinical trials. However, comprehensive real-world studies in the …

Laboratory safety from a randomized 16-week phase III study of dupilumab in children aged 6 months to 5 years with moderate-to-severe atopic dermatitis

AS Paller, EC Siegfried, MJ Cork, A Wollenberg… - Pediatric Drugs, 2023 - Springer
Abstract Background and Objective Previous studies of dupilumab for the treatment of
moderate-to-severe atopic dermatitis in adults and adolescents, and severe atopic dermatitis …