[HTML][HTML] Mediation analysis methods used in observational research: a scoping review and recommendations

JJM Rijnhart, SJ Lamp, MJ Valente… - BMC medical research …, 2021 - Springer
Background Mediation analysis methodology underwent many advancements throughout
the years, with the most recent and important advancement being the development of causal …

Mediation analysis in epidemiology: methods, interpretation and bias

L Richiardi, R Bellocco, D Zugna - International journal of …, 2013 - academic.oup.com
In epidemiological studies it is often necessary to disentangle the pathways that link an
exposure to an outcome. Typically the aim is to identify the total effect of the exposure on the …

Mediational E-values: approximate sensitivity analysis for unmeasured mediator–outcome confounding

LH Smith, TJ VanderWeele - Epidemiology, 2019 - journals.lww.com
Background: Mediation analysis is a powerful tool for understanding mechanisms, but
conclusions about direct and indirect effects will be invalid if there is unmeasured …

[HTML][HTML] Mediation analysis with a time-to-event outcome: a review of use and reporting in healthcare research

L Lapointe-Shaw, Z Bouck, NA Howell, T Lange… - BMC medical research …, 2018 - Springer
Background Mediation analysis tests whether the relationship between two variables is
explained by a third intermediate variable. We sought to describe the usage and reporting of …

[HTML][HTML] Mediation analysis: a practitioner's guide

TJ VanderWeele - Annual review of public health, 2016 - annualreviews.org
This article provides an overview of recent developments in mediation analysis, that is,
analyses used to assess the relative magnitude of different pathways and mechanisms by …

[HTML][HTML] Comparison of methods for the analysis of relatively simple mediation models

JJM Rijnhart, JWR Twisk, MJM Chinapaw… - Contemporary clinical …, 2017 - Elsevier
Background/aims Statistical mediation analysis is an often used method in trials, to unravel
the pathways underlying the effect of an intervention on a particular outcome variable …

CMAverse: a suite of functions for reproducible causal mediation analyses

B Shi, C Choirat, BA Coull, TJ VanderWeele… - Epidemiology, 2021 - journals.lww.com
In this letter, we introduce CMAverse, an R package that provides a suite of functions for
reproducible causal mediation analysis including directed acyclic graph (DAG) visualization …

[HTML][HTML] Statistical mediation analysis for models with a binary mediator and a binary outcome: The differences between causal and traditional mediation analysis

JJM Rijnhart, MJ Valente, HL Smyth, DP MacKinnon - Prevention Science, 2021 - Springer
Mediation analysis is an important statistical method in prevention research, as it can be
used to determine effective intervention components. Traditional mediation analysis defines …

[HTML][HTML] Sensitivity analysis for direct and indirect effects in the presence of exposure-induced mediator-outcome confounders

TJ VanderWeele, Y Chiba - Epidemiology, biostatistics, and public …, 2014 - ncbi.nlm.nih.gov
Questions of mediation are often of interest in reasoning about mechanisms, and methods
have been developed to address these questions. However, these methods make strong …

Interventional effects for mediation analysis with multiple mediators

S Vansteelandt, RM Daniel - Epidemiology, 2017 - journals.lww.com
The mediation formula for the identification of natural (in) direct effects has facilitated
mediation analyses that better respect the nature of the data, with greater consideration of …