Background Liver cancer is the third leading cause of cancer-related deaths worldwide, and
hepatocellular carcinoma (HCC) is the most common type of liver cancer. Transarterial …

The activation of signaling pathways induced by Toll-like receptor (TLR) has been
demonstrated to play essential roles in multiple liver diseases. Toll-interacting protein …

Background Toll-like receptors (TLRs) are key factors in the innate immune system and
initiate the inflammatory response to foreign pathogens such as bacteria, fungi and viruses …

Abstract Toll-like receptors (TLRs), mainly expressing in human immune related cells and
epithelial cells, play an essential role in the host defense against microbes by recognizing …

Expression of Toll-interacting protein (Tollip), a potent TLR modulator, decreases in patients
with inflammatory bowel diseases (IBD), whereas Tollip−/− mice are susceptible to colitis …

Abstract Background Toll-like receptors (TLRs) play an important role in innate immunity by
sensing a variety of pathogens and inducing acquired immunity. To test our hypothesis that …

Abstract Toll‑like receptor 2 (TLR2), is an important pattern recognition receptor which
serves a role in chronic inflammation of the liver. However, the role of TLR2 in the …

Platinum‐based chemotherapy drugs play a very important role in the treatment of patients
with advanced colorectal cancer, but the drug resistance of platinum‐based chemotherapy …

Toll-like receptor 3 (TLR3) is a pattern-recognizing receptor that is involved in immune
signaling and plays a crucial role in survival by being able to recognize various viral …

Toll-like receptors (TLRs) can specifically identify pathogen-associated molecular patterns
(PAMPs) by recognizing structural patterns in diverse microbial molecules, and can provide …