The avian coronavirus spike protein

INA Wickramasinghe, SJ Van Beurden, E Weerts… - Virus research, 2014 - Elsevier
Avian coronaviruses of the genus Gammacoronavirus are represented by infectious
bronchitis virus (IBV), the coronavirus of chicken. IBV causes a highly contagious disease …

[HTML][HTML] Mapping of the receptor-binding domain and amino acids critical for attachment in the spike protein of avian coronavirus infectious bronchitis virus

N Promkuntod, REW Van Eijndhoven, G De Vrieze… - Virology, 2014 - Elsevier
The infection of the avian coronavirus infectious bronchitis virus (IBV) is initiated by the
binding of the spike glycoprotein S to sialic acids on the chicken host cell. In this study we …

Binding of avian coronavirus spike proteins to host factors reflects virus tropism and pathogenicity

INA Wickramasinghe, RP De Vries, A Gröne… - Journal of …, 2011 - Am Soc Microbiol
The binding of viruses to host cells is the first step in determining tropism and pathogenicity.
While avian infectious bronchitis coronavirus (IBV) infection and avian influenza A virus …

Contributions of the S2 spike ectodomain to attachment and host range of infectious bronchitis virus

N Promkuntod, INA Wickramasinghe, G de Vrieze… - Virus research, 2013 - Elsevier
The spike protein is the major viral attachment protein of the avian coronavirus infectious
bronchitis virus (IBV) and ultimately determines viral tropism. The S1 subunit of the spike is …

Coronavirus spike protein and tropism changes

RJG Hulswit, CAM De Haan, BJ Bosch - Advances in virus research, 2016 - Elsevier
Coronaviruses (CoVs) have a remarkable potential to change tropism. This is particularly
illustrated over the last 15 years by the emergence of two zoonotic CoVs, the severe acute …

Three amino acid changes in avian coronavirus spike protein allow binding to kidney tissue

KM Bouwman, LM Parsons, AJ Berends… - Journal of …, 2020 - Am Soc Microbiol
Infectious bronchitis virus (IBV) infects ciliated epithelial cells in the chicken respiratory tract.
While some IBV strains replicate locally, others can disseminate to various organs, including …

[HTML][HTML] Glycosylation of the viral attachment protein of avian coronavirus is essential for host cell and receptor binding

LM Parsons, KM Bouwman, H Azurmendi… - Journal of Biological …, 2019 - ASBMB
Avian coronaviruses, including infectious bronchitis virus (IBV), are important respiratory
pathogens of poultry. The heavily glycosylated IBV spike protein is responsible for binding to …

[HTML][HTML] Spike protein fusion peptide and feline coronavirus virulence

HW Chang, HF Egberink, R Halpin… - Emerging infectious …, 2012 - ncbi.nlm.nih.gov
Coronaviruses are well known for their potential to change their host or tissue tropism,
resulting in unpredictable new diseases and changes in pathogenicity; severe acute …

Coronavirus spike proteins in viral entry and pathogenesis

TM Gallagher, MJ Buchmeier - Virology, 2001 - ncbi.nlm.nih.gov
Coronaviruses comprise a large and diverse family of enveloped, positive-stranded RNA
viruses. The Coronaviridae exhibit broad host range, infecting many mammalian and avian …

Coronavirus avian infectious bronchitis virus

D Cavanagh - Veterinary research, 2007 - hal.science
Infectious bronchitis virus (IBV), the coronavirus of the chicken (Gallus gallus), is one of the
foremost causes of economic loss within the poultry industry, affecting the performance of …