This study aimed to discover the novel noninvasive biomarkers for the diagnosis of
pulmonary tuberculosis (TB). We applied iTRAQ 2D LC‐MS/MS technique to investigate …

Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis is a chronic disease.
Currently, there are no sufficiently validated biomarkers for early diagnosis of TB infection. In …

The epidemic of pulmonary tuberculosis (TB), especially multidrug-resistance tuberculosis
(MDR-TB) presented a major challenge for TB treatment today. We performed iTRAQ …

Severe pulmonary tuberculosis (STB) is a life‑threatening condition with high economic and
social burden. The present study aimed to screen for distinct proteins in different stages of …

Multidrug‐resistant tuberculosis (MDR‐TB), defined as tuberculosis (TB) resistant to at least
isoniazid and rifampicin, is a major concern of TB control worldwide. However, the diagnosis …

Tuberculosis (TB) is a major comorbidity in HIV patients as well as a serious co-epidemic.
Traditional detection methods are not effective or sensitive for the detection of …

Background: New technologies for the early detection of tuberculosis (TB) are urgently
needed. Pathological changes within an organ might be reflected in proteomic patterns in …

The protein composition of sputum most faithfully reflects the state of the lungs. The aim of
this study was to determine whether relative qualitative and quantitative differences in …

Background Noninvasive and convenient biomarkers for early diagnosis of tuberculosis (TB)
remain an urgent need. The aim of this study was to discover and identify potential …

Background Pulmonary tuberculosis (TB) is a serious disease burden worldwide, and its
effective early diagnosis is still facing challenges. Knowledge, acquired from multi-omics …