Quantitative Hyperpolarized 129Xe Gas exchange MRI: Development and Applications

Z Wang - 2020 - search.proquest.com
Pulmonary diseases are one of the leading causes of death and contribute to major
healthcare cost in the United States. However, clinical treatment of these diseases has long …

Translational imaging of pulmonary gas-exchange using hyperpolarized 129Xe magnetic resonance imaging

SS Kaushik - 2014 - search.proquest.com
The diagnosis and treatment of pulmonary diseases still rely on pulmonary function tests that
offer archaic or insensitive biomarkers of lung structure and function. As a consequence …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

A single‐breath‐hold protocol for hyperpolarized 129Xe ventilation and gas exchange imaging

PJ Niedbalski, MM Willmering, RP Thomen… - NMR in …, 2023 - Wiley Online Library
Hyperpolarized 129Xe MRI (Xe‐MRI) is increasingly used to image the structure and
function of the lungs. Because 129Xe imaging can provide multiple contrasts (ventilation …

[PDF][PDF] Hyperpolarized 129Xe MRI and spectroscopy in healthy control subjects reveals age-related changes in measurements of pulmonary gas exchange

D Mummy, A Swaminathan, E Bier… - Proceedings of the …, 2022 - dgmummy.com
Conclusion Various metrics derived from hyperpolarized 129Xe gas exchange MRI and
spectroscopy have been proposed as potential markers of disease progression and therapy …

Repeatability of regional pulmonary functional metrics of Hyperpolarized 129Xe dissolved‐phase MRI

AD Hahn, J Kammerman, M Evans… - Journal of Magnetic …, 2019 - Wiley Online Library
Background MRI of hyperpolarized 129Xenon (HP 129Xe) is increasingly utilized for
investigating pulmonary function. The solubility of HP 129Xe in lung tissue, blood plasma …

Positive Results from Two Randomized Phase III Trials Assessing Hyperpolarized129Xenon Gas MRI as a Measure of Regional Lung Function as Compared to …

YMM Shim, J Mata, M Hartwig… - B39. DYSPNEA …, 2020 - atsjournals.org
Introduction: Hyperpolarized 129Xe MRI (HPX) is a promising diagnostic modality for 3D
imaging of pulmonary function without radiation. It overcomes the lack of regionality of …

Quantitative Spectral Contrast in Hyperpolarized 129 Xe Pulmonary MRI

SH Robertson - 2016 - search.proquest.com
Abstract Hyperpolarized (HP) 129 Xe MRI has emerged as a viable tool for evaluating lung
function without ionizing radiation. HP 129 Xe has already been used to image ventilation …

Improving techniques and clinical utility of hyperpolarized 129-Xenon lung MRI

J Plummer - 2024 - rave.ohiolink.edu
Hyperpolarized 129 Xe MRI is a monumental imaging advancement for studying pulmonary
structure and function. Following an inhalation of hyperpolarized 129 Xe gas, it enables …

Using the full power of multiple hyperpolarized 129Xe contrasts to interrogate aging, smoking, and COPD

PJ Niedbalski, M Castro - European Radiology, 2024 - Springer
Chronic obstructive pulmonary disease (COPD) remains one of the top causes of death
worldwide. With an aim toward precision medicine, pulmonary imaging is increasingly used …