The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
SF Janssen, TGMF Gorgels, WD Ramdas… - Progress in retinal and …, 2013 - Elsevier
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
[HTML][HTML] Genome-wide association study of primary open angle glaucoma risk and quantitative traits
J Gibson, H Griffiths, G De Salvo, M Cole, A Jacob… - Molecular …, 2012 - ncbi.nlm.nih.gov
Purpose Primary open angle glaucoma (POAG) is a characteristic optic neuropathy which
progresses to irreversible vision loss. Few genes have been detected that influence POAG …
progresses to irreversible vision loss. Few genes have been detected that influence POAG …
Molecular complexity of primary open angle glaucoma: current concepts
K Ray, S Mookherjee - Journal of genetics, 2009 - Springer
Glaucoma is a group of heterogeneous optic neuropathies with complex genetic basis.
Among the three principle subtypes of glaucoma, primary open angle glaucoma (POAG) …
Among the three principle subtypes of glaucoma, primary open angle glaucoma (POAG) …
Update on the genetics of primary open-angle glaucoma
Affecting nearly 80 million individuals, glaucoma is the number one cause of irreversible
blindness in the world. This ocular disease describes a set of optic neuropathies of which …
blindness in the world. This ocular disease describes a set of optic neuropathies of which …
Clinical implications of recent advances in primary open-angle glaucoma genetics
H Choquet, JL Wiggs, AP Khawaja - Eye, 2020 - nature.com
Over the last decade, genetic studies, including genome-wide association studies (GWAS),
have accelerated the discovery of genes and genomic regions contributing to primary open …
have accelerated the discovery of genes and genomic regions contributing to primary open …
Characterizing the “POAGome”: A bioinformatics-driven approach to primary open-angle glaucoma
ID Danford, LD Verkuil, DJ Choi, DW Collins… - Progress in retinal and …, 2017 - Elsevier
Primary open-angle glaucoma (POAG) is a genetically, physiologically, and phenotypically
complex neurodegenerative disorder. This study addressed the expanding collection of …
complex neurodegenerative disorder. This study addressed the expanding collection of …
Major review: Molecular genetics of primary open-angle glaucoma
Y Liu, RR Allingham - Experimental eye research, 2017 - Elsevier
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
Primary open angle glaucoma genetics: The common variants and their clinical associations
A Trivli, MI Zervou, GN Goulielmos… - Molecular …, 2020 - spandidos-publications.com
Glaucoma is a group of progressive optic neuropathies that have in common characteristic
optic nerve head changes, loss of retinal ganglion cells and visual field defects. Among the …
optic nerve head changes, loss of retinal ganglion cells and visual field defects. Among the …
An updated review on the genetics of primary open angle glaucoma
K Abu-Amero, AA Kondkar, KV Chalam - International journal of …, 2015 - mdpi.com
Epidemiological studies suggest that by 2020 the prevalence of primary open angle
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …
Gene mapping for primary open angle glaucoma
Primary open angle glaucoma (POAG) is a leading cause of visual impairment and
blindness worldwide. To date, at least 20 genetic loci for POAG have been reported. Only 3 …
blindness worldwide. To date, at least 20 genetic loci for POAG have been reported. Only 3 …