Background Bronchiectasis can result from infectious, genetic, immunological and allergic
causes. 60–80% of cases are idiopathic, but a well-recognised genetic cause is the motile …

Background It is estimated that 1–13% of cases of bronchiectasis in adults globally are
attributable to primary ciliary dyskinesia (PCD) but many adult patients with bronchiectasis …

Primary ciliary dyskinesia (PCD) is a rare inherited autosomal recessive or X-linked disorder
that mainly affects lungs. Dysfunction of respiratory cilia causes symptoms such as chronic …

Bronchiectasis represents the final pathway of several infectious, genetic, immunologic or
allergic disorders. Accurate and prompt identification of the underlying cause is a key …

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder reflecting
abnormalities in the structure and function of motile cilia and flagella, causing impairment of …

Background Primary ciliary dyskinesia (PCD) is a motile ciliopathy characterised by
otosinopulmonary infections. Inheritance is commonly autosomal recessive, with extensive …

Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder leading to chronic
upper and lower airway disease. Fundamental data on epidemiology, clinical presentation …

Rationale: In primary ciliary dyskinesia, factors leading to disease heterogeneity are poorly
understood. Objectives: To describe early lung disease progression in primary ciliary …

Significant advances have been made in the diagnosis of patients with primary ciliary
dyskinesia (PCD) including centralised services [ 1–3], European consensus guidelines [4] …

Background Primary ciliary dyskinesia (PCD) is a multigenic autosomal recessive condition
affecting respiratory tract and other organs where ciliary motility is required. The extent of its …