The dermal sheath (DS) is a population of mesenchyme-derived skin cells with emerging
importance for skin homeostasis. The DS includes hair follicle dermal stem cells, which …

Two critical cell types necessary to produce and maintain hair follicles are fibroblasts, which
reside in the dermal papilla (DP) and dermal sheath (DS), and keratinocytes, including hair …

The dermis harbors distinct mesenchymal stem cell (MSC) populations, which play equally
important roles as epidermal stem cells in skin homeostasis and regeneration. However, to …

Despite the remarkable regenerative capacity of mammalian skin, an adult dermal stem cell
has not yet been identified. Here, we investigated whether skin-derived precursors (SKPs) …

Skin aging is accompanied by hair loss due to impairments in hair follicle (HF) epithelial
progenitor cells and their mesenchymal niche. This inductive mesenchyme, called dermal …

The skin constantly renews itself throughout adult life, and the hair follicle undergoes a
perpetual cycle of growth and degeneration. Stem cells (SCs) residing in the epidermis and …

The epidermis is the outermost layer of mammalian skin and comprises a multilayered
epithelium, the interfollicular epidermis, with associated hair follicles, sebaceous glands …

The mesenchymal components of the hair follicle—the dermal papilla (DP) and dermal
sheath (DS)—are maintained by hair follicle dermal stem cells, but the position of this stem …

In healthy individuals, skin integrity is maintained by epidermal stem cells which self‐renew
and generate daughter cells that undergo terminal differentiation. It is currently unknown …

Skin homeostasis is orchestrated by dozens of cell types that together direct stem cell
renewal, lineage commitment, and differentiation. Here, we use single-cell RNA sequencing …