Medical device related infections are a significant and growing source of morbidity and
mortality. Biofilm formation is a common feature of medical device infections that is not …

Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

Bacterial biofilms are highly protected surface attached communities of bacteria that typically
cause chronic infections. To address their recalcitrance to antibiotics and minimise side …

Biofilms are formed by the attachment of single or mixed microbial communities to a variety
of biological and/or synthetic surfaces. Biofilm micro-organisms benefit from many …

To tackle the emerging antibiotic resistance crisis, novel antimicrobial approaches are
urgently needed. Bacterial communities (biofilms) are a particular concern in this context …

Importance of the field: Current antibiotics have classically been developed to treat
infections involving planktonic bacterial populations in acute infection settings and are …

This commentary highlights several avenues currently being pursued in research labs to the
development of new anti-biofilm pharmaceuticals. There is a real need for alternative …

Biofilms have attracted increasing attention in recent years. Many bacterial infections are
associated with biofilm formation. A bacterial biofilm is an aggregated membrane-like …

In order to colonize abiotic surfaces, bacteria and fungi undergo a profound change in their
biology to form biofilms: communities of microbes embedded into a matrix of secreted …

The problem of drug resistance is very worrying and ever increasing. Resistance is due not
only to the reckless use of antibiotics but also to the fact that pathogens are able to adapt to …