Chemokines modulate the tumour microenvironment in pituitary neuroendocrine tumours
P Marques, S Barry, E Carlsen, D Collier… - Acta neuropathologica …, 2019 - Springer
Non-tumoural cells within the tumour microenvironment (TME) influence tumour
proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary …
proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary …
The tumour microenvironment of pituitary neuroendocrine tumours
P Marques, AB Grossman, M Korbonits - Frontiers in Neuroendocrinology, 2020 - Elsevier
The tumour microenvironment (TME) includes a variety of non-neoplastic cells and non-
cellular elements such as cytokines, growth factors and enzymes surrounding tumour cells …
cellular elements such as cytokines, growth factors and enzymes surrounding tumour cells …
Immune landscape of pituitary tumors reveals association between macrophages and gonadotroph tumor invasion
M Principe, M Chanal, MD Ilie, A Ziverec… - The Journal of …, 2020 - academic.oup.com
Abstract Purpose Pituitary neuroendocrine tumors (PitNETs) are frequent intracranial
neoplasms that present heterogenic characteristics. Little is known about the immune cell …
neoplasms that present heterogenic characteristics. Little is known about the immune cell …
The microenvironment of pituitary tumors—biological and therapeutic implications
The tumor microenvironment (TME) includes resident and infiltrative non-tumor cells, as well
as blood and lymph vessels, extracellular matrix molecules, and numerous soluble factors …
as blood and lymph vessels, extracellular matrix molecules, and numerous soluble factors …
Immune cell infiltrates in pituitary adenomas: more macrophages in larger adenomas and more T cells in growth hormone adenomas
JQ Lu, B Adam, AS Jack, A Lam, RW Broad… - Endocrine pathology, 2015 - Springer
Tumor immune microenvironment has been gradually recognized as a key contributor to
tumor development, progression, and control. Immune cell infiltrates in brain tumors have …
tumor development, progression, and control. Immune cell infiltrates in brain tumors have …
The microenvironment of pituitary adenomas: biological, clinical and therapeutical implications
The microenvironment of pituitary adenomas (PAs) includes a range of non-tumoral cells,
such as immune and stromal cells, as well as cell signaling molecules such as cytokines …
such as immune and stromal cells, as well as cell signaling molecules such as cytokines …
Analysis of tumor angiogenesis and immune microenvironment in non-functional pituitary endocrine tumors
Cavernous sinus (CS) invasion is an aggressive behavior exhibited by pituitary
neuroendocrine tumors (PitNETs). The cause of CS invasion in PitNETs has not been fully …
neuroendocrine tumors (PitNETs). The cause of CS invasion in PitNETs has not been fully …
Pituitary tumour fibroblast-derived cytokines influence tumour aggressiveness
P Marques, S Barry, E Carlsen… - Endocrine-Related …, 2019 - erc.bioscientifica.com
Tumour-associated fibroblasts (TAFs) are key elements of the tumour microenvironment, but
their role in pituitary neuroendocrine tumours (PitNETs) has been little explored. We …
their role in pituitary neuroendocrine tumours (PitNETs) has been little explored. We …
[HTML][HTML] Stratifying nonfunctional pituitary adenomas into two groups distinguished by macrophage subtypes
Tumor-associated macrophages (TAMs) polarize to M1 and M2 subtypes exerting anti-
tumoral and pro-tumoral effects, respectively. To date, little is known about TAMs, their …
tumoral and pro-tumoral effects, respectively. To date, little is known about TAMs, their …
The tumor microenvironment in neuroendocrine tumors: biology and therapeutic implications
M Cives, E Pelle, D Quaresmini, FM Rizzo… - …, 2019 - karger.com
Neuroendocrine tumors (NETs) include a heterogeneous group of malignancies arising in
the diffuse neuroendocrine system and characterized by indolent growth. Complex …
the diffuse neuroendocrine system and characterized by indolent growth. Complex …