Background: Research on opioid-free anesthesia has increased in recent years; however, it
has never been determined whether it is more beneficial than opioid anesthesia. This meta …

Background: Postoperative nausea and vomiting (PONV) is a common complication, that
can reduce patient satisfaction and may lead to serious consequences, such as wound …

Opioids are administered peri‐operatively for postoperative analgesia, and intra‐operatively
to control the sympathetic response to surgical stimuli, frequently as a surrogate for …

Introduction: Balanced anaesthesia relies, amongst other drugs, on the administration of
opioids in the perioperative period as antinociceptive agents. There is no clear evidence that …

The use of opioids as anti-pain medications in the perioperative period is influenced by
intraoperative anaesthesia. There is no conclusive evidence that intraoperative opioids …

Background Although opioids are commonly prescribed in clinical anaesthesia, the
significant side effects attributed to their overuse are raising increasing concerns. One way …

Study objective Opioid-free anaesthesia may enhance postoperative recovery by reducing
opioid-related side effects such as nausea, hyperalgesia or tolerance. The objective was to …

Study objective To evaluate all available evidence thus far on opioid based versus opioid-
free anesthesia and its effect on acute and chronic postoperative pain. Design Systematic …

Background Postoperative nausea and vomiting (PONV) is a common complication after
general anaesthesia and is associated with morbidity and prolonged length of stay. Growing …

Introduction: Opioid Free Anesthesia (OFA) is a relatively new technique that has been
questioned due to the lack of evidence regarding its benefit-risk balance. Methods: Four …