[HTML][HTML] A novel oxidative stress-and ferroptosis-related gene prognostic signature for distinguishing cold and hot tumors in colorectal cancer

X Wang, Y Xu, L Dai, Z Yu, M Wang, S Chan… - Frontiers in …, 2022 - frontiersin.org
Oxidative stress and ferroptosis exhibit crosstalk in many types of human diseases, including
malignant tumors. We aimed to develop an oxidative stress-and ferroptosis-related gene …

[HTML][HTML] Screening of ferroptosis-related genes with prognostic effect in colorectal cancer by bioinformatic analysis

D Hu, Z Zhou, J Wang, K Zhu - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Colorectal cancer (CRC) remains a common malignant tumor of digestive tract with high
incidence rate and high mortality in the worldwide. The current clinical treatments of CRC …

[HTML][HTML] An original ferroptosis-related gene signature effectively predicts the prognosis and clinical status for colorectal cancer patients

Y Shao, H Jia, L Huang, S Li, C Wang, B Aikemu… - Frontiers in …, 2021 - frontiersin.org
Background Colorectal cancer (CRC) is one of the most common malignant tumors in the
world. Ferroptosis is a newly defined form of cell death, distinguished by different …

Ferroptosis-related genes are potential prognostic molecular markers for patients with colorectal cancer

Y Liu, F Guo, W Guo, Y Wang, W Song, T Fu - Clinical and experimental …, 2021 - Springer
Ferroptosis is a newly discovered programmed cell death that plays a vital role in the
occurrence and development of tumors. However, little is known about its prognostic value …

[HTML][HTML] A ferroptosis-related gene signature identified as a novel prognostic biomarker for colon cancer

X Qi, R Wang, Y Lin, D Yan, J Zuo, J Chen… - Frontiers in genetics, 2021 - frontiersin.org
Background Colon cancer (CC) is a common gastrointestinal malignant tumor with high
heterogeneity in clinical behavior and response to treatment, making individualized survival …

[HTML][HTML] Prognostic and predictive models for left-and right-colorectal cancer patients: a bioinformatics analysis based on ferroptosis-related genes

Y Chen, H Li - Frontiers in Oncology, 2022 - frontiersin.org
Background Left-and right-sided colorectal cancer (LCRC, RCRC) are significantly different
in epidemiology and clinical manifestations and have altered outcomes. However, as a hot …

[HTML][HTML] Role of ferroptosis-related genes in prognostic prediction and tumor immune microenvironment in colorectal carcinoma

C Yang, S Huang, F Cao, Y Zheng - PeerJ, 2021 - peerj.com
Materials and Methods Of 1,192 CRC patients with complete information from the public
datasets (TCGA CRC, GEO GSE39582 and GSE17538 cohorts) were selected for analysis …

Development and Validation of a Novel Ferroptosis‐Related Gene Signature for Predicting Prognosis and the Immune Microenvironment in Gastric Cancer

F Wang, C Chen, WP Chen, ZL Li… - BioMed research …, 2021 - Wiley Online Library
Ferroptosis is a mode of regulated cell death that depends on iron and plays pivotal roles in
regulating various biological processes in human cancers. However, the role of ferroptosis …

Low ferroptosis score predicts chemotherapy responsiveness and immune‐activation in colorectal cancer

Y Lv, QY Feng, ZY Zhang, P Zheng, D Zhu… - Cancer …, 2023 - Wiley Online Library
Background Existing studies for ferroptosis and prognosis in colorectal cancer (CRC) were
limited. In this study, we aim to investigate the prognostic role of ferroptosis markers in …

[HTML][HTML] Construction and validation of a novel ferroptosis-related lncRNA signature to predict prognosis in colorectal cancer patients

W Zhang, D Fang, S Li, X Bao, L Jiang, X Sun - Frontiers in genetics, 2021 - frontiersin.org
Background: Colorectal cancer (CRC) ranks as the third most common malignancy
worldwide but a reliable prognostic biomarker of CRC is still lack. Thus, the purpose of our …