Major depressive disorder and aneurysm: A genetic study of association and causality

J Zhuang, X Yu, H Liu, J Li, P Tang, Y Zhang… - Journal of Affective …, 2024 - Elsevier
Background Association between depression and aneurysm has been implicated but the
specific role of depression in aneurysm remains unclear. We aimed to comprehensively …

Appraising the causal association among depression, anxiety and intracranial aneurysms: Evidence from genetic studies

M Turhon, A Maimaiti, A Abulaiti, Y Dilixiati… - Journal of Affective …, 2024 - Elsevier
Background The risk of intracranial aneurysms (IAs) is increased in individuals with
depression and anxiety. This indicates that depression and anxiety may contribute to the …

Causal association between depression and intracranial aneurysms: a bidirectional two-sample Mendelian randomization study

J Wu, H Sun, J Ma - Frontiers in Neurology, 2024 - frontiersin.org
Background Although observational studies have suggested a bidirectional relation
between depression and intracranial aneurysms (IAs), their causal relations remain unclear …

Relationship between mental disorders and abdominal aortic aneurysm: insights from genetic perspectives

MG Deng, C Chai, K Wang, JQ Nie, F Liu, Y Liang… - medRxiv, 2024 - medrxiv.org
Objective: To explore the correlation or potential causation between mental disorders
[depression, schizophrenia (SCZ), bipolar disorder (BIP)], and abdominal aortic aneurysm …

Investigating causal relationships between psychiatric traits and intracranial aneurysms: a bi-directional two-sample Mendelian randomization study

P Peng, Z Chen, X Zhang, Z Guo, F Dong, Y Xu… - Frontiers in …, 2021 - frontiersin.org
Background Despite psychiatric traits were associated with intracranial aneurysms (IAs) in
observational studies, their causal relationships remain largely undefined. We aimed to …

Overlapping common genetic architecture between major depressive disorders and anxiety and stress-related disorders

L Mei, Y Gao, M Chen, X Zhang, W Yue… - Progress in Neuro …, 2022 - Elsevier
Major depressive disorders (MDDs) and anxiety and stress-related disorders (ASRDs) have
overlapping symptoms and high rates of comorbidity. However, the underlying mechanisms …

Shared genetic liability and causal associations between major depressive disorder and cardiovascular diseases

F Zhang, H Cao, A Baranova - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Major depressive disorder (MDD) is phenotypically associated with cardiovascular diseases
(CVD). We aim to investigate mechanisms underlying relationships between MDD and CVD …

Evaluation of bi-directional causal association between depression and cardiovascular diseases: a Mendelian randomization study

GHY Li, CL Cheung, AKK Chung… - Psychological …, 2022 - cambridge.org
BackgroundDepression and cardiovascular disease (CVD) are associated with each other
but their relationship remains unclear. We aim to determine whether genetic predisposition …

Association between psychiatric disorders and intracranial aneurysms: evidence from Mendelian randomization analysis

S Bao, Z Xing, S He, X Hu, J Yang, B Zhou - Frontiers in Neurology, 2024 - frontiersin.org
Objective Several studies have explored the relationship between intracranial aneurysms
and psychiatric disorders; nevertheless, the causal connection remains ambiguous. This …

Causal association between major depressive disorder and coronary heart disease: a two-sample bidirectional mendelian randomization study

Q Xu, C Chen, R You, L Ni, S Chen, B Peng - BMC Medical Genomics, 2023 - Springer
Background Major depressive disorder (MDD) is a highly heterogeneous mental illness and
a major public health problem worldwide. A large number of observational studies have …