[HTML][HTML] Gestational factors throughout fetal neurodevelopment: the serotonin link

SI Hanswijk, M Spoelder, L Shan, MMM Verheij… - International journal of …, 2020 - mdpi.com
Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders.
Fetal 5-HT levels can be influenced by several gestational factors, such as maternal …

Effects of prenatal maternal stress on serotonin and fetal development

J St-Pierre, L Laurent, S King, C Vaillancourt - Placenta, 2016 - Elsevier
Fetuses are exposed to many environmental perturbations that can influence their
development. These factors can be easily identifiable such as drugs, chronic diseases or …

[HTML][HTML] Placental serotonin: implications for the developmental effects of SSRIs and maternal depression

JC Velasquez, N Goeden, A Bonnin - Frontiers in cellular …, 2013 - frontiersin.org
In addition to its role in the pathophysiology of numerous psychiatric disorders, increasing
evidence points to serotonin (5-HT) as a crucial molecule for the modulation of …

Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology

L Booij, RE Tremblay, M Szyf, C Benkelfat - Journal of psychiatry and …, 2015 - jpn.ca
Background: Despite more than 60 years of research in the role of serotonin (5-HT) in
psychopathology, many questions still remain. From a developmental perspective, studies …

Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain

A Bonnin, P Levitt - Neuroscience, 2011 - Elsevier
In addition to its role in neurotransmission, embryonic serotonin (5-HT) has been implicated
in the regulation of neurodevelopmental processes. For example, we recently showed that a …

The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric Outcomes

AG Paquette, CJ Marsit - Journal of Cellular Biochemistry, 2014 - Wiley Online Library
The serotonin receptor 5‐HT2A (encoded by HTR2A) is an important regulator of fetal brain
development and adult cognitive function. Environmental signals that induce epigenetic …

[HTML][HTML] Refining the role of 5-HT in postnatal development of brain circuits

A Teissier, M Soiza-Reilly, P Gaspar - Frontiers in cellular …, 2017 - frontiersin.org
Changing serotonin (5-hydroxytryptamine, 5-HT) brain levels during critical periods in
development has long-lasting effects on brain function, particularly on later …

Fetal serotonin signaling: setting pathways for early childhood development and behavior

TF Oberlander - Journal of Adolescent Health, 2012 - Elsevier
Finely tuning levels of the key neurotransmitter serotonin (5-hydroxytryptamine [5-HT])
during early life is essential for brain development and setting pathways for health and …

Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation

S Migliarini, G Pacini, B Pelosi, G Lunardi… - Molecular …, 2013 - nature.com
Despite increasing evidence suggests that serotonin (5-HT) can influence neurogenesis,
neuronal migration and circuitry formation, the precise role of 5-HT on central nervous …

Maternal inflammation disrupts fetal neurodevelopment via increased placental output of serotonin to the fetal brain

N Goeden, J Velasquez, KA Arnold… - Journal of …, 2016 - Soc Neuroscience
Maternal inflammation during pregnancy affects placental function and is associated with
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …