The immunology of acute stroke

A Chamorro, A Meisel, AM Planas, X Urra… - Nature reviews …, 2012 - nature.com
Recent clinical and experimental studies have highlighted a complex role for the immune
system in the pathophysiological changes that occur after acute stroke. Sensors of the innate …

Immune mechanisms of stroke

T Magnus, H Wiendl, C Kleinschnitz - Current opinion in …, 2012 - journals.lww.com
Immune mechanisms of stroke : Current Opinion in Neurology Immune mechanisms of
stroke : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …

The immunology of stroke: from mechanisms to translation

C Iadecola, J Anrather - Nature medicine, 2011 - nature.com
Immunity and inflammation are key elements of the pathobiology of stroke, a devastating
illness second only to cardiac ischemia as a cause of death worldwide. The immune system …

Stroke-induced immunodepression: experimental evidence and clinical relevance

U Dirnagl, J Klehmet, JS Braun, H Harms, C Meisel… - Stroke, 2007 - Am Heart Assoc
Stroke affects the normally well-balanced interplay of the 2 supersystems: the nervous and
the immune system. Recent research elucidated some of the involved signals and …

Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?

A Rayasam, M Hsu, JA Kijak, L Kissel… - …, 2018 - Wiley Online Library
Stroke is one of the leading causes of death and disability worldwide. The long‐standing
dogma that stroke is exclusively a vascular disease has been questioned by extensive …

The immune system and stroke: from current targets to future therapy

K Malone, S Amu, AC Moore… - Immunology and cell …, 2019 - Wiley Online Library
Stroke is a major cause of morbidity and mortality worldwide. Despite the intensive search
for new therapies, hundreds of agents targeting various pathophysiological mechanisms …

Immunological consequences of ischemic stroke

A Vogelgesang, KJ Becker… - Acta Neurologica …, 2014 - Wiley Online Library
The treatment of ischemic stroke is one of the great challenges in modern neurology. The
localization and the size of the infarct determine the long‐term disability of stroke survivors …

Infection after acute ischemic stroke: a manifestation of brain-induced immunodepression

A Chamorro, X Urra, AM Planas - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Infection after experimental focal ischemia may result from brain-
induced immunodepression, but it is unsettled whether a similar syndrome occurs in human …

Immune interventions in stroke

Y Fu, Q Liu, J Anrather, FD Shi - Nature Reviews Neurology, 2015 - nature.com
Approaches for the effective management of acute stroke are sparse, and many measures
for brain protection fail. However, our ability to modulate the immune system and modify the …

Stroke and the immune system: from pathophysiology to new therapeutic strategies

R Macrez, C Ali, O Toutirais, B Le Mauff… - The Lancet …, 2011 - thelancet.com
Stroke is the second most common cause of death worldwide and a major cause of acquired
disability in adults. Despite tremendous progress in understanding the pathophysiology of …