Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

D Stolz, T Mkorombindo, DM Schumann, A Agusti… - The Lancet, 2022 - thelancet.com
Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

Management of severe COPD

EFM Wouters - The Lancet, 2004 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide, and the burden of the disorder will continue to increase over the next 20 years …

The future of chronic obstructive pulmonary disease treatment—difficulties of and barriers to drug development

FJ Martinez, JF Donohue, SI Rennard - The Lancet, 2011 - thelancet.com
Although chronic obstructive pulmonary disease (COPD) is a major global health problem
with a rising incidence and morbidity, few pharmacotherapeutic advances have been made …

Prospects for new drugs for chronic obstructive pulmonary disease

PJ Barnes, TT Hansel - The Lancet, 2004 - thelancet.com
No currently available treatments have been shown to slow the progression of chronic
obstructive pulmonary disease (COPD) or suppress the inflammation in small airways and …

Early chronic obstructive pulmonary disease: definition, assessment, and prevention

SI Rennard, MB Drummond - The Lancet, 2015 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide. COPD, however, is a heterogeneous collection of diseases with differing causes …

Global burden of COPD: risk factors, prevalence, and future trends

DM Mannino, AS Buist - The Lancet, 2007 - thelancet.com
Chronic obstructive pulmonary disease (COPD) continues to be an important cause of
morbidity, mortality, and health-care costs worldwide. It is a global health issue, with …

Chronic obstructive pulmonary disease and comorbidities

M Decramer, W Janssens - The Lancet Respiratory Medicine, 2013 - thelancet.com
Results of epidemiological studies have shown that chronic obstructive pulmonary disease
(COPD) is frequently associated with comorbidities, the most serious and prevalent being …

Controversies in treatment of chronic obstructive pulmonary disease

KF Rabe, JA Wedzicha - The Lancet, 2011 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a chronic disorder with substantial
comorbidity and major effects attributable to the high morbidity and mortality rates. Despite …

Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management

PG Woodruff, A Agusti, N Roche, D Singh, FJ Martinez - The Lancet, 2015 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a common, complex, and heterogeneous
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …

Chronic obstructive pulmonary disease: from unjustified nihilism to evidence-based optimism

BR Celli - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) has been associated with a nihilistic
attitude. On the basis of current evidence, this nihilistic attitude is totally unjustified. The …