Processing in cortical circuits is driven by combinations of cortical and subcortical inputs.
These inputs are often conceptually categorized as bottom-up, conveying sensory …

The cortex is organized as a hierarchical processing structure. Feedback from higher levels
of the hierarchy, known as top-down signals, have been shown to be involved in attentional …

In primary visual cortex, a subset of neurons responds when a particular stimulus is
encountered in a certain location in visual space. This activity can be modeled using a visual …

Sensory computations performed in the neocortex involve layer six (L6) cortico-cortical (CC)
and cortico-thalamic (CT) signaling pathways. Developing an understanding of the …

Because layer 6 of the cerebral cortex receives direct thalamic input and provides
projections back to the thalamus, it is in a unique position to influence thalamocortical …

Layer 6 of monkey V1 contains a physiologically and anatomically diverse population of
excitatory pyramidal neurons. Distinctive arborization patterns of axons and dendrites within …

The planning and control of sensory-guided movements requires the integration of multiple
sensory streams. Although the information conveyed by different sensory modalities is often …

Efficient visuomotor behavior depends on integrated processing by the visual and motor
systems of the cerebral cortex. Yet, many previous cortical neurophysiology studies have …

Initial anatomical and physiological studies suggested that sensory information relayed from
the periphery by the thalamus is serially processed in primary sensory cortical areas. It is …

Brain function relies on the coordination of activity across multiple, recurrently connected
brain areas. For instance, sensory information encoded in early sensory areas is relayed to …