Guanidine–curcumin complex-loaded amine-functionalised hollow mesoporous silica nanoparticles for breast cancer therapy

TM Viswanathan, K Chitradevi, A Zochedh… - Cancers, 2022 - mdpi.com
Simple Summary The combination of guanidine carbonate and curcumin-loaded hollow
mesoporous silica nanoparticles (GuC-HMSNAP) can be used as a therapeutic and to …

Combinatorial delivery of gallium (III) nitrate and curcumin complex-loaded hollow mesoporous silica nanoparticles for breast cancer treatment

T Mohan Viswanathan, V Krishnakumar… - Nanomaterials, 2022 - mdpi.com
The main aims in the development of a novel drug delivery vehicle is to efficiently carry
therapeutic drugs in the body's circulatory system and successfully deliver them to the …

[HTML][HTML] In vitro efficacy of curcumin-loaded amine-functionalized mesoporous silica nanoparticles against MCF-7 breast cancer cells

Z Mohebian, M Babazadeh… - Advanced Pharmaceutical …, 2023 - ncbi.nlm.nih.gov
Purpose: Mesoporous silica nanoparticles (MSNs) have drawn substantial interest as drug
nanocarriers for breast cancer therapy. Nevertheless, because of the hydrophilic surfaces …

Mesoporous silica nanoparticle-based intelligent drug delivery system for bienzyme-responsive tumour targeting and controlled release

Y Zhang, J Xu - Royal Society open science, 2018 - royalsocietypublishing.org
This paper proposes a novel type of multifunctional envelope-type mesoporous silica
nanoparticle (MSN) to achieve cancer cell targeting and drug-controlled release. In this …

[HTML][HTML] An ingenious non-spherical mesoporous silica nanoparticle cargo with curcumin induces mitochondria-mediated apoptosis in breast cancer (MCF-7) cells

L Harini, S Srivastava, GP Gnanakumar… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Curcumin delivery to cancer cells is challenging due to its hydrophobic nature, low bio
distribution and low availability. Many nano vehicles suffer from low stability and toxicity, and …

[HTML][HTML] Functionalised mesoporous silica nanoparticles with excellent cytotoxicity against various cancer cells for pH-responsive and controlled drug delivery

SS Park, MH Jung, YS Lee, JH Bae, SH Kim, CS Ha - Materials & design, 2019 - Elsevier
Mesoporous silica nanoparticles (MSNs) modified with Pt and carboxyl groups were
designed and the drug molecule-release behaviour was studied by loading cisplatin as a …

Hollow mesoporous silica nanoparticles facilitated drug delivery via cascade pH stimuli in tumor microenvironment for tumor therapy

J Liu, Z Luo, J Zhang, T Luo, J Zhou, X Zhao, K Cai - Biomaterials, 2016 - Elsevier
To efficiently deliver anti-cancer drug to tumor site and reduce its toxic side effects on normal
tissues, a polyethylene glycol (PEG) shielding and tumor microenvironment triggering …

Decapeptide functionalized targeted mesoporous silica nanoparticles with doxorubicin exhibit enhanced apoptotic effect in breast and prostate cancer cells

P Tambe, P Kumar, KM Paknikar… - International journal of …, 2018 - Taylor & Francis
Background Considering the increase in cancer cases and number of deaths per year
worldwide, development of potential therapeutics is imperative. Mesoporous silica …

Targeted delivery of curcumin in breast cancer cells via hyaluronic acid modified mesoporous silica nanoparticle to enhance anticancer efficiency

S Ghosh, S Dutta, A Sarkar, M Kundu, PC Sil - Colloids and Surfaces B …, 2021 - Elsevier
Curcumin (C) is a natural antioxidant which has many beneficial effects. However, poor
bioavailability and less water solubility render it unsuitable as an anti-cancer drug. Herein …

A dual-responsive, hyaluronic acid targeted drug delivery system based on hollow mesoporous silica nanoparticles for cancer therapy

L Huang, J Liu, F Gao, Q Cheng, B Lu… - Journal of Materials …, 2018 - pubs.rsc.org
In this study, a novel drug delivery system (HMSNs-SS-HA) based on hollow mesoporous
silica nanoparticles (HMSNs) was developed for delivering anticancer drugs (eg …