Background Hepatocyte nuclear factor‐1α gene (HNF1A) single nucleotide polymorphisms
(SNPs) have been associated with serum lipid traits in several previous genome‐wide …

BACKGROUND: Coronary artery disease (CAD) is the one of the most common heart
diseases, being the main factor of mortality and morbidity worldwide. CAD has been known …

Background—The transcription factor hepatocyte nuclear factor (HNF)-1α regulates the
activity of a number of genes involved in innate immunity, blood coagulation, lipid and …

Background Ischemic stroke is a life-threatening condition due to obstructed blood supply of
the brain. Elevation of plasma C-reactive protein, an important inflammatory marker, was …

BACKGROUND: The level of C-reactive protein (CRP), an inflammatory biomarker that
predicts future cardiovascular events, is a heritable trait that has been associated with …

Background C-reactive protein is a well established marker of inflammation and has been
used to predict future cardiovascular disease. It is still controversial if it plays an active role in …

Background Recent genome-wide association studies (GWAS) have identified several
single nucleotide polymorphisms (SNPs) that were associated with blood lipid levels in …

Aims/hypothesis According to genome-wide association studies (GWAS) a locus in the
HNF1A gene has pleiotropic effects on several metabolic traits. In a large single-centre study …

Background and Purpose: Stroke is a complex disease with multiple genetic and
environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to …

Background and aims Liver biomarkers and metabolic associated fatty liver disease
(MAFLD) have been shown to be associated with cardiovascular disease (CVD). However …