Association of the HNF1A polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke
YJ Zhou, RX Yin, SC Hong, Q Yang… - The journal of gene …, 2017 - Wiley Online Library
Background Hepatocyte nuclear factor‐1α gene (HNF1A) single nucleotide polymorphisms
(SNPs) have been associated with serum lipid traits in several previous genome‐wide …
(SNPs) have been associated with serum lipid traits in several previous genome‐wide …
A molecular case-control study of association of HNF1A gene polymorphisms (rs2259816 and rs7310409) with risk of coronary artery disease in Iranian patients
SA Barzi, SMH Ghaderian… - Human …, 2017 - content.iospress.com
BACKGROUND: Coronary artery disease (CAD) is the one of the most common heart
diseases, being the main factor of mortality and morbidity worldwide. CAD has been known …
diseases, being the main factor of mortality and morbidity worldwide. CAD has been known …
Common Coding Variants of the HNF1A Gene Are Associated With Multiple Cardiovascular Risk Phenotypes in Community-Based Samples of Younger and Older …
AP Reiner, MD Gross, CS Carlson… - Circulation …, 2009 - Am Heart Assoc
Background—The transcription factor hepatocyte nuclear factor (HNF)-1α regulates the
activity of a number of genes involved in innate immunity, blood coagulation, lipid and …
activity of a number of genes involved in innate immunity, blood coagulation, lipid and …
Association study of C-reactive protein associated gene HNF1A with ischemic stroke in Chinese population
H Shi, S Leng, H Liang, Y Zheng, L Chen - BMC medical genetics, 2016 - Springer
Background Ischemic stroke is a life-threatening condition due to obstructed blood supply of
the brain. Elevation of plasma C-reactive protein, an important inflammatory marker, was …
the brain. Elevation of plasma C-reactive protein, an important inflammatory marker, was …
Effect of obesity on the association between common variations in the HNF1A gene region and C-reactive protein level in Taiwanese
LA Hsu, YL Ko, MS Teng, S Wu, HH Chou, PY Chang… - Clinica Chimica …, 2011 - Elsevier
BACKGROUND: The level of C-reactive protein (CRP), an inflammatory biomarker that
predicts future cardiovascular events, is a heritable trait that has been associated with …
predicts future cardiovascular events, is a heritable trait that has been associated with …
Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the ludwigshafen risk and …
ME Kleber, TB Grammer, W Renner, W März - BMC medical genetics, 2010 - Springer
Background C-reactive protein is a well established marker of inflammation and has been
used to predict future cardiovascular disease. It is still controversial if it plays an active role in …
used to predict future cardiovascular disease. It is still controversial if it plays an active role in …
Associations of lipid levels susceptibility loci with coronary artery disease in Chinese population
X Wang, Y Han, NH Cui, J Gao, J Yang… - Lipids in Health and …, 2015 - Springer
Background Recent genome-wide association studies (GWAS) have identified several
single nucleotide polymorphisms (SNPs) that were associated with blood lipid levels in …
single nucleotide polymorphisms (SNPs) that were associated with blood lipid levels in …
Pleiotropic effects of HNF1A rs1183910 in a population-based study of 60,283 individuals
KH Allin, BG Nordestgaard - Diabetologia, 2014 - Springer
Aims/hypothesis According to genome-wide association studies (GWAS) a locus in the
HNF1A gene has pleiotropic effects on several metabolic traits. In a large single-centre study …
HNF1A gene has pleiotropic effects on several metabolic traits. In a large single-centre study …
Genome-wide association study meta-analysis of stroke in 22 000 individuals of African descent identifies novel associations with stroke
Background and Purpose: Stroke is a complex disease with multiple genetic and
environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to …
environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to …
Liver biomarkers, genetic and lifestyle risk factors in relation to risk of cardiovascular disease in Chinese
Background and aims Liver biomarkers and metabolic associated fatty liver disease
(MAFLD) have been shown to be associated with cardiovascular disease (CVD). However …
(MAFLD) have been shown to be associated with cardiovascular disease (CVD). However …
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