Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

Tuberculosis (TB) is a large global health problem, in part because of the long period of
coevolution of the pathogen, Mycobacterium tuberculosis, and its human host. A major factor …

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), remains a major
worldwide health problem that causes more than 2 million deaths annually. In addition, an …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Tuberculosis (TB) vaccine research has reached a unique point in time. Breakthrough
findings in both the basic immunology of Mycobacterium tuberculosis infection and the …

There is an urgent need for new and better vaccines against tuberculosis (TB). Current
vaccine design strategies are generally focused on the enhancement of cell-mediated …

The vaccine discovery paradigm in tuberculosis (TB) has been to mimic the natural immune
response to infection. With an emphasis on interferon (IFN)-γ as the main protective …

Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …

Despite the overwhelming success of immunization in reducing, and even eliminating, the
global threats posed by a wide spectrum of infectious diseases, attempts to do the same for …

Tuberculosis (TB) remains a serious threat to public health, causing 2 million deaths
annually world-wide. The control of TB has been hindered by the requirement of long …