Bone is a tissue with constant remodeling, where osteoblasts form and osteoclasts degrade
bone. Both cell types are highly specialized in their function and both form from precursors …

Bone formation and degradation are perfectly coordinated. In case of an imbalance of these
processes diseases occur associated with exaggerated formation of new bone or bone loss …

Reactive oxygen species (ROS) generated by the NADPH oxidase (Nox) enzymes are
important short‐range signaling molecules. They have been extensively studied in the …

ROS are implicated in bone diseases. NADPH oxidase 4 (NOX4), a constitutively active
enzymatic source of ROS, may contribute to the development of such disorders. Therefore …

Increased oxidative stress plays an important role in the pathophysiology of many diseases
such as atherosclerosis, diabetes mellitus, myocardial infarction and heart failure. In addition …

Significance: Skin protects the body from dehydration, pathogens, and external mutagens.
NADPH oxidases are central components for regulating the cellular redox balance. There is …

Reactive oxygen species are mostly viewed to cause oxidative damage to various cells and
induce organ dysfunction after ischemia‐reperfusion injury. However, they are also …

The superoxide generating enzyme NADPH oxidase has received much attention as a
major cause of oxidative stress underlying vascular disease. However, there is increasing …

Reactive oxygen species (ROS) are produced by all vascular cells and regulate the major
physiological functions of the vasculature. Production and removal of ROS are tightly …

Oxidative stress induced by long‐term glucocorticoid (GC) use weakens the repair capacity
of bone tissue. Nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) …