[HTML][HTML] Emerging roles for IL-11 in inflammatory diseases

KY Fung, C Louis, RD Metcalfe, CC Kosasih, IP Wicks… - Cytokine, 2022 - Elsevier
Abstract Interleukin-11 (IL-11) is a cytokine that has been strongly implicated in the
pathogenesis of fibrotic diseases and solid malignancies. Elevated IL-11 expression is also …

Interleukin-13: A promising therapeutic target for autoimmune disease

YM Mao, CN Zhao, J Leng, RX Leng, DQ Ye… - Cytokine & growth factor …, 2019 - Elsevier
Abstract Interleukin-13 (IL-13) was previously thought to be a redundant presence of IL-4,
but in recent years its role in immunity, inflammation, fibrosis, and allergic diseases has …

[HTML][HTML] Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons?

H Mühl - Frontiers in immunology, 2013 - frontiersin.org
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share
characteristic properties such as defined structural features, usage of IL-10R2 as one …

Interleukin-15: a new cytokine target for the treatment of inflammatory diseases

IB McInnes, JA Gracie - Current opinion in pharmacology, 2004 - Elsevier
Interleukin (IL)-15 is a pleiotropic pro-inflammatory cytokine that is expressed in several
inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary …

Hiding in plain sight: interleukin-11 emerges as a master regulator of fibrosis, tissue integrity, and stromal inflammation

SA Cook, S Schafer - Annual Review of Medicine, 2020 - annualreviews.org
Interleukin (IL)-11 is upregulated in a wide variety of fibro-inflammatory diseases such as
systemic sclerosis, rheumatoid arthritis, pulmonary fibrosis, inflammatory bowel disease …

IL-17 signaling in host defense and inflammatory diseases

Y Qian, Z Kang, C Liu, X Li - Cellular & molecular immunology, 2010 - nature.com
Abstract Interleukin (IL)-17, the signature cytokine secreted by T helper (Th) 17 cells, plays
important roles in host defense against extracellular bacterial infection and fungal infection …

IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases

X Song, Y Qian - Cellular signalling, 2013 - Elsevier
Inflammation is the immediate protective response of the body to pathogen invasions,
allergen challenges, chemical exposures or physical injuries. Acute inflammation usually …

Interleukin‐6 as a therapeutic target in candidate inflammatory diseases

N Nishimoto - Clinical Pharmacology & Therapeutics, 2010 - Wiley Online Library
Interleukin (IL)‐6 is a multifunctional cytokine that regulates immune response, inflammation,
and hematopoiesis. Although IL‐6 plays several important physiological roles, deregulated …

Emerging roles for Interleukin-11 in disease

PM Nguyen, SM Abdirahman, TL Putoczki - Growth Factors, 2019 - Taylor & Francis
Abstract Interleukin (IL)-11 belongs to the IL-6 family of cytokines, discovered over 30 years
ago. While early studies focused on the ability of IL-11 to stimulate megakaryocytopoiesis …

[HTML][HTML] Targeting interleukin-17 in chronic inflammatory disease: A clinical perspective

P Zwicky, S Unger, B Becher - Journal of Experimental Medicine, 2020 - rupress.org
Chronic inflammatory diseases like psoriasis, Crohn's disease (CD), multiple sclerosis (MS),
rheumatoid arthritis (RA), and others are increasingly recognized as disease entities, where …