Multiple sclerosis epidemiological trends in Italy highlight the environmental risk factors

M Puthenparampil, P Perini, R Bergamaschi… - Journal of …, 2022 - Springer
Italy is definitely a high-risk country for multiple sclerosis (MS). Over the last 50 years,
several epidemiological studies, including longitudinal surveys, have disclosed that MS …

Multiple sclerosis prevalence among Sardinians: further evidence against the latitude gradient theory

M Pugliatti, S Sotgiu, G Solinas, P Castiglia… - Neurological …, 2001 - Springer
A descriptive epidemiological survey was extended to the whole province of Sassari,
northern Sardinia between latitudes 40° 30'N and 41° N. Results showed a crude total …

Epidemiology of multiple sclerosis in Northwestern Sardinia: further evidence for higher frequency in Sardinians compared to other Italians

G Rosati, I Aiello, MI Pirastru, L Mannu, G Sanna… - …, 1996 - karger.com
The Sardinians are an ethnically homogeneous population, having a genetic structure quite
different from that of all other Italian and European populations. All epidemiological studies …

Prevalence and incidence of multiple sclerosis in Salerno (southern Italy) and its province

G Iuliano, R Napoletano - European journal of neurology, 2008 - Wiley Online Library
Many multiple sclerosis (MS) prevalence studies in Italian northern and central areas, since
1980, have put Italy in a high risk zone; none concerns southern Italy. The MS registry of …

Multiple sclerosis in the province of Ferrara: evidence for an increasing trend

E Granieri, NT Economou, R De Gennaro, MR Tola… - Journal of …, 2007 - Springer
Background Epidemiological studies on the distribution of multiple sclerosis (MS) conducted
in the Mediterranean area in the last two decades have disclosed a significant increase in …

Multiple sclerosis epidemiology in Sardinia: evidence for a true increasing risk

M Pugliatti, S Sotgiu, G Solinas… - Acta neurologica …, 2001 - Wiley Online Library
Objectives–To update prevalence and incidence rates of MS among Sardinians. Materials
and methods–The present work is a “spider” kind of population based survey, conducted …

Increasing incidence of multiple sclerosis in the province of Sassari, northern Sardinia

M Pugliatti, T Riise, MA Sotgiu, S Sotgiu, WM Satta… - …, 2005 - karger.com
Sardinia is a high-risk area for multiple sclerosis (MS), with prevalence rates of 150 per
100,000 population. The study included 689 MS patients (female-male ratio 2.6) with …

The prevalence of multiple sclerosis in central Italy

E Millefiorini, A Cortese, S Di Rezze… - Multiple Sclerosis …, 2010 - journals.sagepub.com
Background: The prevalence of multiple sclerosis varies considerably throughout the world.
Objective: To better define the prevalence of MS in central Italy. Methods: This is a …

Epidemiology of multiple sclerosis in south-western Sardinia

E Cocco, C Sardu, R Massa, E Mamusa… - Multiple Sclerosis …, 2011 - journals.sagepub.com
Background: Sardinia is a known high-risk area for multiple sclerosis (MS), but no data for
south-western Sardinia (SWS) are available. SWS has a genetically homogeneous …

Multiple sclerosis complexity in selected populations: the challenge of Sardinia, insular Italy1

S Sotgiu, M Pugliatti, A Sanna, A Sotgiu… - European journal of …, 2002 - Wiley Online Library
Several lines of evidence indicate a genetic contribution to multiple sclerosis (MS) both in
terms of predisposition to the disease and of immunological mechanisms which are known …