Abstract Thiazolidine-2, 4-dione is an extensively explored heterocyclic nucleus for
designing of novel agents implicated for a wide variety of pathophysiological conditions, that …

Diabetes or diabetes mellitus is a complex or polygenic disorder, which is characterized by
increased levels of glucose (hyperglycemia) and deficiency in insulin secretion or resistance …

2, 4-Thiazolidinedione (2, 4-TZD) is a versatile pharmacophore, a privileged scaffold, and a
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …

The promising activity shown by compounds containing thiazolidine-2, 4-dione nucleus in
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …

Thiazolidinedione (2, 4‐TZD), commonly known as glitazone, is a ubiquitous heterocyclic
pharmacophore possessing a plethora of pharmacological activities and offering a vast …

Thiazolidinedione (TZD) is a privileged and highly utilised scaffold for the development of
pharmaceutically active compounds. This sulfur‐containing heterocycle is a versatile …

In case of metabolic disorder like Diabetes mellitus (DM), a number of key enzymes are
abnormally expressed and hence they might be excellent targets for antidiabetic drug …

In the modern scenario, thiazolidinone scaffold has emerged as a very potent scaffold as per
its clinical significance concerned. It has attracted the keen interest of the researchers due to …

Thiazolidinediones are sulfur containing pentacyclic compounds that are widely found
throughout nature in various forms. Thiazolidinedione nucleus is present in numerous …

A series of new thiazolopyrimidine analogues were conveniently synthesized by one-pot
multicomponent condensation reaction of ethyl acetoacetate, 2-aminothiazole and …