[HTML][HTML] Immunotherapeutic progress and application of bispecific antibody in cancer

J Kang, T Sun, Y Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Bispecific antibodies (bsAbs) are artificial antibodies with two distinct antigen-binding sites
that can bind to different antigens or different epitopes on the same antigen. Based on a …

Immunoglobulin gamma‐like therapeutic bispecific antibody formats for tumor therapy

S Chen, L Li, F Zhang, Y Wang, Y Hu… - Journal of Immunology …, 2019 - Wiley Online Library
Bispecific antibodies (BsAbs) are a sort of dual functional proteins with specific binding to
two distinct targets, which have become a focus of interest in antibody engineering and drug …

Bispecific antibody (bsAb) construct formats and their application in cancer therapy

DO Acheampong - Protein and Peptide Letters, 2019 - ingentaconnect.com
Development of cancers mostly involves more than one signal pathways, because of the
complicated nature of cancer cells. As such, the most effective treatment option is the one …

Current Status of the Research and Development of Bispecific Antibodies

SI Kwon - Biomedical Science Letters, 2020 - koreascience.kr
A bispecific antibody (BsAb) is an artificial protein containing two kinds of specific antigen
binding sites. BsAb can connect target cells to functional cells or molecules, and thus …

[HTML][HTML] Bispecific antibodies: from research to clinical application

J Ma, Y Mo, M Tang, J Shen, Y Qi, W Zhao… - Frontiers in …, 2021 - frontiersin.org
Bispecific antibodies (BsAbs) are antibodies with two binding sites directed at two different
antigens or two different epitopes on the same antigen. The clinical therapeutic effects of …

Construction and production of an IgG-like tetravalent bispecific antibody for enhanced therapeutic efficacy

D Lu, Z Zhu - Therapeutic Antibodies: Methods and Protocols, 2009 - Springer
In past years, both laboratory and early clinical studies have demonstrated that bispecific
antibodies (BsAbs) may have significant potential application in cancer therapy either by …

Bispecific antibodies for cancer therapy

N Hollander - 2009 - Future Medicine
Bispecific antibodies, in contrast to conventional monoclonal antibodies, can bind
simultaneously two different antigens. Taking advantage of this virtue, they are mostly …

Bispecific antibodies: an innovative arsenal to hunt, grab and destroy cancer cells

C Grandjenette, M Dicato… - Current pharmaceutical …, 2015 - ingentaconnect.com
Targeted cellular immunotherapy with bifunctional antibodies (bsAbs) has emerged as a
promising therapeutic approach for cancer over the last two decades. Progress in antibody …

Bispecific antibody and its clinical applications in cancer

Y Xu, C Yang, Z Zhu - Chinese Science Bulletin, 2001 - Springer
Bispecific antibody (BsAb) usually consists of two different antigen-binding arms, by which it
is capable of simultaneously binding to target cells and effector cells, and can directly …

Bispecific antibodies poised to deliver wave of cancer therapies.

C Sheridan - Nature Biotechnology, 2021 - go.gale.com
Bispecific antibodies poised to deliver wave of cancer therapies. - Document - Gale OneFile:
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