International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family
Transient receptor potential (TRP) channels are a large family of ion channel proteins,
surpassed in number in mammals only by voltage-gated potassium channels. TRP channels …
surpassed in number in mammals only by voltage-gated potassium channels. TRP channels …
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
B Nilius, A Szallasi - Pharmacological reviews, 2014 - ASPET
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
Advances in TRP channel drug discovery: from target validation to clinical studies
AP Koivisto, MG Belvisi, R Gaudet… - Nature reviews Drug …, 2022 - nature.com
Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …
Transient receptor potential (TRP) channels: a clinical perspective
Y Kaneko, A Szallasi - British journal of pharmacology, 2014 - Wiley Online Library
Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
TRP (transient receptor potential) ion channel family: Structures, biological functions and therapeutic interventions for diseases
M Zhang, Y Ma, X Ye, N Zhang, L Pan… - Signal Transduction and …, 2023 - nature.com
Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels
The transient receptor potential (TRP1) ion channels are named after the role of the
channels in Drosophila phototransduction. The mammalian genes are encoded by at least …
channels in Drosophila phototransduction. The mammalian genes are encoded by at least …
[HTML][HTML] Molecular mechanism of TRP channels
J Zheng - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
Transient receptor potential (TRP) channels are cellular sensors for a wide spectrum of
physical and chemical stimuli. They are involved in the formation of sight, hearing, touch …
physical and chemical stimuli. They are involved in the formation of sight, hearing, touch …
TRP ion channels in the nervous system
MM Moran, H Xu, DE Clapham - Current opinion in neurobiology, 2004 - Elsevier
The transient receptor potential (TRP) superfamily comprises a group of non-selective cation
channels that sense and respond to changes in their local environments. TRP channels are …
channels that sense and respond to changes in their local environments. TRP channels are …
International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels
The transient receptor potential (TRP) proteins are six transmembrane-containing subunits
that combine to form cation-selective ion channels. TRP channels are present in yeast …
that combine to form cation-selective ion channels. TRP channels are present in yeast …
Transient receptor potential channels as therapeutic targets
MM Moran, MA McAlexander, T Bíró… - Nature reviews Drug …, 2011 - nature.com
Transient receptor potential (TRP) cation channels have been among the most aggressively
pursued drug targets over the past few years. Although the initial focus of research was on …
pursued drug targets over the past few years. Although the initial focus of research was on …