The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL

Z Li, TC Chao, KY Chang, N Lin… - Proceedings of the …, 2014 - National Acad Sciences
Thousands of large intergenic noncoding RNAs (lincRNAs) have been identified in the
mammalian genome, many of which have important roles in regulating a variety of biological …

Cytokines and long noncoding RNAs

S Carpenter, KA Fitzgerald - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Cytokines and long noncoding RNAs (lncRNAs) are intertwined in the regulatory circuit
controlling immunity. lncRNA expression levels are altered following cytokine stimulation in …

The how and why of lncRNA function: an innate immune perspective

EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

[HTML][HTML] A long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages

S Ma, Z Ming, AY Gong, Y Wang, X Chen, G Hu… - The FASEB …, 2017 - ncbi.nlm.nih.gov
Long intergenic noncoding RNAs (lincRNAs) are long noncoding transcripts (> 200 nt) from
the intergenic regions of annotated protein-coding genes. We report here that the lincRNA …

The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4

V Ranzani, G Rossetti, I Panzeri, A Arrigoni… - Nature …, 2015 - nature.com
Long noncoding RNAs are emerging as important regulators of cellular functions, but little is
known of their role in the human immune system. Here we investigated long intergenic …

A long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation

MK Atianand, W Hu, AT Satpathy, Y Shen, EP Ricci… - Cell, 2016 - cell.com
Long intergenic noncoding RNAs (lincRNAs) are important regulators of gene expression.
Although lincRNAs are expressed in immune cells, their functions in immunity are largely …

Long non-coding RNAs in innate and adaptive immunity

TM Aune, CF Spurlock III - Virus research, 2016 - Elsevier
Long noncoding RNAs (lncRNAs) represent a newly discovered class of regulatory
molecules that impact a variety of biological processes in cells and organ systems. In …

Immunobiology of long noncoding RNAs

MK Atianand, DR Caffrey… - Annual review of …, 2017 - annualreviews.org
The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene
regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that …

Long non-coding RNAs and the innate immune response

MR Hadjicharalambous, MA Lindsay - Non-coding RNA, 2019 - mdpi.com
Innate immunity provides the initial defence against infection and it is now clear that long
non-coding RNAs (lncRNAs) are important regulators of this response. Following activation …

Long non-coding RNAs in the regulation of the immune response

JA Heward, MA Lindsay - Trends in immunology, 2014 - cell.com
It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …