Mitoquinone attenuates vascular calcification by suppressing oxidative stress and reducing apoptosis of vascular smooth muscle cells via the Keap1/Nrf2 pathway
L Cui, Q Zhou, X Zheng, B Sun, S Zhao - Free Radical Biology and …, 2020 - Elsevier
Oxidative stress and apoptosis of vascular smooth muscle cells (VSMCs) are key to vascular
calcification in patients with chronic kidney disease (CKD). The mitochondria-targeted …
calcification in patients with chronic kidney disease (CKD). The mitochondria-targeted …
Mitoquinone protects podocytes from angiotensin II‐induced mitochondrial dysfunction and injury via the Keap1‐Nrf2 signaling pathway
Z Zhu, W Liang, Z Chen, J Hu, J Feng… - Oxidative Medicine …, 2021 - Wiley Online Library
Podocyte mitochondrial dysfunction plays a critical role in the pathogenesis of chronic
kidney disease (CKD). Previous studies demonstrated that excessive mitochondrial fission …
kidney disease (CKD). Previous studies demonstrated that excessive mitochondrial fission …
Quercetin attenuates vascular calcification by inhibiting oxidative stress and mitochondrial fission
L Cui, Z Li, X Chang, G Cong, L Hao - Vascular pharmacology, 2017 - Elsevier
Vascular calcification is a strong independent predictor of increased cardiovascular
morbidity and mortality and has a high prevalence among patients with chronic kidney …
morbidity and mortality and has a high prevalence among patients with chronic kidney …
Peroxisome proliferator-activated receptor-γ coactivator-1α inhibits vascular calcification through sirtuin 3-mediated reduction of mitochondrial oxidative stress
H Feng, JY Wang, B Yu, X Cong, WG Zhang… - Antioxidants & redox …, 2019 - liebertpub.com
Aims: Vascular calcification is associated with cardiovascular death in patients with chronic
kidney disease (CKD). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) …
kidney disease (CKD). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) …
Curcumin attenuates osteogenic differentiation and calcification of rat vascular smooth muscle cells
M Hou, Y Song, Z Li, C Luo, JS Ou, H Yu, J Yan… - Molecular and Cellular …, 2016 - Springer
Vascular calcification has been considered as a biological process resembling bone
formation involving osteogenic differentiation. It is a major risk factor for cardiovascular …
formation involving osteogenic differentiation. It is a major risk factor for cardiovascular …
Mitochondrial targeted antioxidant SKQ1 ameliorates acute kidney injury by inhibiting ferroptosis
J Song, J Sheng, J Lei, W Gan… - Oxidative Medicine and …, 2022 - Wiley Online Library
Emerging evidence suggests that ferroptosis is highly correlated with the pathogenesis of
acute kidney injury (AKI). Ferroptosis, an iron‐dependent form of cell death, is manifested by …
acute kidney injury (AKI). Ferroptosis, an iron‐dependent form of cell death, is manifested by …
Cyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway
YW Du, XK Li, TT Wang, L Zhou, HR Li, L Feng, H Ma… - Molecular …, 2023 - Springer
Background Ferroptosis, which is characterized by lipid peroxidation and iron accumulation,
is closely associated with the pathogenesis of acute renal injury (AKI). Cyanidin-3-glucoside …
is closely associated with the pathogenesis of acute renal injury (AKI). Cyanidin-3-glucoside …
Mitochondria‐targeted antioxidant mitoquinone maintains mitochondrial homeostasis through the Sirt3‐dependent pathway to mitigate oxidative damage caused by …
H Mao, Y Zhang, Y Xiong, Z Zhu… - … Medicine and Cellular …, 2022 - Wiley Online Library
Mitochondrial dysfunction is a critical factor contributing to oxidative stress and apoptosis in
ischemia‐reperfusion (I/R) diseases. Mitoquinone (MitoQ) is a mitochondria‐targeted …
ischemia‐reperfusion (I/R) diseases. Mitoquinone (MitoQ) is a mitochondria‐targeted …
α‐Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway
H Kim, HJ Kim, K Lee, JM Kim, HS Kim… - Journal of cellular …, 2012 - Wiley Online Library
Vascular calcification is prevalent in patients with chronic kidney disease and leads to
increased cardiovascular morbidity and mortality. Although several reports have implicated …
increased cardiovascular morbidity and mortality. Although several reports have implicated …
Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress, and apoptosis
Ischemia/reperfusion (IR) is a common cause of acute kidney injury (AKI). However, effective
therapies for IR-induced AKI are lacking. Hyperoside is an active constituent in the flowers of …
therapies for IR-induced AKI are lacking. Hyperoside is an active constituent in the flowers of …
相关搜索
- oxidative stress vascular calcification
- oxidative stress mitochondrial fission
- muscle cells vascular calcification
- oxidative stress muscle cells
- survival pathway vascular calcification
- keap1 nrf2 signaling pathway
- antioxidant mitoquinone oxidative damage
- coactivator 1α vascular calcification
- oxidative stress protective effect
- mitochondrial fission vascular calcification
- receptor γ vascular calcification
- lipoic acid vascular calcification
- keap1 nrf2 mitochondrial dysfunction
- muscle cells osteogenic differentiation
- oxidative stress impaired biogenesis
- oxidative stress ischemia reperfusion