Extracellular Vesicles Derived from Gut Microbiota, Especially Akkermansia muciniphila, Protect the Progression of Dextran Sulfate Sodium-Induced Colitis

C Kang, M Ban, EJ Choi, HG Moon, JS Jeon, DK Kim… - PloS one, 2013 - journals.plos.org
Gut microbiota play an important part in the pathogenesis of mucosal inflammation, such as
inflammatory bowel disease (IBD). However, owing to the complexity of the gut microbiota …

Commensal bacteria-derived extracellular vesicles suppress ulcerative colitis through regulating the macrophages polarization and remodeling the gut microbiota

L Liang, C Yang, L Liu, G Mai, H Li, L Wu, M Jin… - Microbial Cell …, 2022 - Springer
Abstract Background The extracellular vesicles (EVs) traffic constitutes an essential pathway
of cellular communication. And the molecules in EVs produced by procaryotes help in …

Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner …

L Gul, D Modos, S Fonseca… - Journal of …, 2022 - Wiley Online Library
The gastrointestinal (GI) tract harbours a complex microbial community, which contributes to
its homeostasis. A disrupted microbiome can cause GI‐related diseases, including …

Intestinal Anti-inflammatory Effects of Outer Membrane Vesicles from Escherichia coli Nissle 1917 in DSS-Experimental Colitis in Mice

MJ Fábrega, A Rodríguez-Nogales… - Frontiers in …, 2017 - frontiersin.org
Escherichia coli Nissle 1917 (EcN) is a probiotic strain with proven efficacy in inducing and
maintaining remission of ulcerative colitis. However, the microbial factors that mediate these …

Versatility of bacterial outer membrane vesicles in regulating intestinal homeostasis

X Wang, S Lin, L Wang, Z Cao, M Zhang, Y Zhang… - Science …, 2023 - science.org
Outer membrane vesicles (OMVs) play vital roles in bacterial communication both
intraspecifically and interspecifically. However, extracellular mechanisms of gut microbiota …

Clostridium butyricum and its derived extracellular vesicles modulate gut homeostasis and ameliorate acute experimental colitis

L Ma, Q Shen, W Lyu, L Lv, W Wang, M Yu… - Microbiology …, 2022 - Am Soc Microbiol
Microbiological treatments are expected to have a role in the future management of
inflammatory bowel disease (IBD). Clostridium butyricum (C. butyricum) is a probiotic …

Anti‐Inflammatory Effect of Clostridium butyricum‐Derived Extracellular Vesicles in Ulcerative Colitis: Impact on Host microRNAs Expressions and Gut Microbiome …

L Ma, W Lyu, Y Song, K Chen, L Lv… - Molecular Nutrition & …, 2023 - Wiley Online Library
Score Probiotics extracellular vesicles (EVs) have shown potential as EV‐based
nanomaterials therapy for the treatment of inflammatory bowel disease (IBD). Although …

[HTML][HTML] Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota

L Tong, H Hao, Z Zhang, Y Lv, X Liang, Q Liu, T Liu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Bovine milk constitutes an essential part of human diet, especially for children,
due to its enrichment of various nutrients. We recently developed an effective protocol for the …

Role of colonic microbiota in the pathogenesis of ulcerative colitis

L Pei, Y Ke, H Zhao, L Wang, C Jia, W Liu, Q Fu… - BMC …, 2019 - Springer
Background Recent studies have found gut microbiota to be closely associated with onset
and perpetuation of UC. Currently, studies about gut microbiota have mainly covered …

Extracellular vesicles produced by the human gut commensal bacterium Bacteroides thetaiotaomicron elicit anti-inflammatory responses from innate immune cells

S Fonseca, AL Carvalho, A Miquel-Clopés… - Frontiers in …, 2022 - frontiersin.org
Bacterial extracellular vesicles (BEVs) produced by gut commensal bacteria have been
proposed to play an important role in maintaining host homeostasis via interactions with the …