Flavokawain A (FKA), a major chalcone in the Kava plant, has recently demonstrated
promising anti-cancer activities. A systematic evaluation of FKA's safety profile has not been …

Chalcones are naturally occurring compounds exhibiting biological activity through multiple
mechanisms. Flavokawain B is one of chalcones found in kava plant. In our studies, we …

Flavokawain B (FKB), a naturally occurring chalcone in kava extracts, has been reported to
possess anticancer activity. However, the effect of FKB on gastric cancer remains unclear …

Background Osteosarcoma (OS) is the most common primary bone malignancy with a high
propensity for local invasion and distant metastasis. Limited by the severe toxicity of …

Ethnopharmacological relevance Flavokawain A, the major chalcone in kava extracts, was
served as beverages for informal social occasions and traditional ceremonials in most South …

Flavokawain A (FKA) is the predominant chalcone identified from the kava plant. We have
previously shown that FKA preferentially inhibits the growth of p53 defective bladder cancer …

Flavokawain B (FKB) is a naturally occurring chalcone that can be isolated through the root
extracts of the kava-kava plant (Piper methysticum). It can also be synthesized chemically to …

Flavokawain C (FKC) is a naturally occurring chalcone which can be found in Kava (Piper
methysticum Forst) root. The present study evaluated the effect of FKC on the growth of …

Consumption of the traditional kava preparation was reported to correlate with low and
uncustomary gender ratios (more cancer in women than men) of cancer incidences in three …

Background The kava-kava plant (Piper methysticum) is traditionally consumed by the
pacific islanders and has been linked to be involved in several biological activities …