[HTML][HTML] Arsenic induces ferroptosis and acute lung injury through mtROS-mediated mitochondria-associated endoplasmic reticulum membrane dysfunction

MD Li, L Fu, BB Lv, Y Xiang, HX Xiang, DX Xu… - Ecotoxicology and …, 2022 - Elsevier
The goal of this study was to analyze whether mitochondria-associated endoplasmic
reticulum membrane (MAMs) dysfunction mediated arsenic (As)-evoked pulmonary …

Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway

S Wei, T Qiu, X Yao, N Wang, L Jiang, X Jia… - Journal of hazardous …, 2020 - Elsevier
Chronic arsenic exposure is a significantly risk factor for pancreatic dysfunction and type 2
diabetes (T2D). Ferroptosis is a newly identified iron-dependent form of oxidative cell death …

Chronic arsenic exposure induces ferroptosis via enhancing ferritinophagy in chicken livers

L Yu, Z Lv, S Li, H Jiang, B Han, X Zheng, Y Liu… - Science of The Total …, 2023 - Elsevier
Arsenic (As) is a well-known pollutant in the environment, whose contamination in
groundwater is a serious threat to animals and humans. Ferroptosis, a form of cell death …

Arsenic induces apoptosis in myoblasts through a reactive oxygen species-induced endoplasmic reticulum stress and mitochondrial dysfunction pathway

YP Yen, KS Tsai, YW Chen, CF Huang, RS Yang… - Archives of …, 2012 - Springer
A pool of myoblasts available for myogenesis is important for skeletal muscle size. The
decreased number of skeletal muscle fibers could be due to the decreased myoblast …

Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated …

TH Lu, TJ Tseng, CC Su, FC Tang, CC Yen, YY Liu… - Toxicology letters, 2014 - Elsevier
Abstract Arsenic (As), a well-known high toxic metal, is an important environmental and
industrial contaminant, and it induces oxidative stress, which causes many adverse health …

Acrylamide induces ferroptosis in HSC-T6 cells by causing antioxidant imbalance of the XCT-GSH-GPX4 signaling and mitochondrial dysfunction

Y Yuan, L Yucai, L Lu, L Hui, P Yong, Y Haiyang - Toxicology Letters, 2022 - Elsevier
Acrylamide (AA) is a heat-induced food contaminant, mainly metabolized by the liver.
Increasing evidences have proved that ferroptosis is linked to the pathogenesis of liver …

Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure

Q Tang, LL Bai, Z Zou, P Meng, Y Xia, S Cheng, S Mu… - Neurotoxicology, 2018 - Elsevier
Ferroptosis is a novel iron-dependent form of cell death implicated in brain pathology.
However, whether arsenite is an inducer of ferroptosis in the neuron remains completely …

Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway

GH Chen, CC Song, K Pantopoulos, XL Wei… - Free Radical Biology …, 2022 - Elsevier
Ferroptosis is a regulated form of cell death induced by iron (Fe)-dependent lipid
peroxidation. At present, the underlying molecular mechanisms remain elusive. Herein, we …

Salvianolic acid A attenuates arsenic-induced ferroptosis and kidney injury via HIF-2α/DUOX1/GPX4 and iron homeostasis

D Yang, X Xia, S Xi - Science of The Total Environment, 2024 - Elsevier
Arsenic (As) is a prevalent pollutant in the environment and causes a high frequency of
kidney disease in areas of high arsenic contamination, but its pathogenic mechanisms have …

Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy

J Xiao, S Zhang, B Tu, X Jiang, S Cheng, Q Tang… - Food and Chemical …, 2021 - Elsevier
Ferroptosis is a novel form of cell death that involves in the pathophysiological process of
diverse brain diseases. However, how arsenite induces ferroptosis in the neuronal cells …