GATA-1-dependent transcription is essential for erythroid differentiation and maturation.
Suppression of programmed cell death is also thought to be critical for this process; …

The induction of Bcl-xL is critical for the survival of late proerythroblasts. The erythroid-
specific transcriptional network that regulates Bcl-xL expression in erythropoiesis remains …

The transcription factor GATA-1 is essential for normal erythropoiesis. By examining in vitro–
differentiated embryonic stem cells, we showed previously that in the absence of GATA-1 …

How cell proliferation subsides as cells terminally differentiate remains largely enigmatic,
although this phenomenon is central to the existence of multicellular organisms. Here, we …

GATA1 is considered as the “master” transcription factor in erythropoiesis. It regulates at the
transcriptional level all aspects of erythroid maturation and function, as revealed by gene …

GATA transcription factor family members GATA1 and GATA2 play crucial roles in the
regulation of lineage-restricted genes during erythroid differentiation. GATA1 is …

Erythropoiesis is the complex, dynamic, and tightly regulated process that generates all
mature red blood cells. To understand this process, we mapped the developmental …

The transcription factor GATA-1 is required for terminal erythroid maturation and functions as
an activator or repressor depending on gene context. Yet its in vivo site selectivity and ability …

Transcription factor GATA-1 is required for erythropoiesis, yet its full actions are unknown.
We performed transcriptome analysis of G1E-ER4 cells, a GATA-1–null erythroblast line that …

Transcription factor GATA-1 plays an important role in gene regulation during the
development of erythroid cells. Several reports suggest that GATA-1 plays multiple roles in …