M2 Macrophage-Derived Exosomal lncRNA MIR4435-2HG Promotes Progression of Infantile Hemangiomas by Targeting HNRNPA1

Z Li, Z Cao, N Li, L Wang, C Fu, R Huo… - International Journal …, 2023 - Taylor & Francis
Purpose Infantile hemangiomas (IHs) are commonly observed benign tumors that can cause
serious complications. M2-polarized macrophages in IHs promote disease progression. In …

[HTML][HTML] Exosome-derived miR-196b-5p facilitates intercellular interaction in infantile hemangioma via down-regulating CDKN1B

QZ Wang, ZL Zhao, C Liu, JW Zheng - Annals of translational …, 2021 - ncbi.nlm.nih.gov
Background Though infantile hemangioma (IH) is a common benign vascular tumor, its
pathogenesis remains unclear. This study explored the function of hemangioma-derived …

[HTML][HTML] Engineered exosomes for targeted delivery of miR-187-3p suppress the viability of hemangioma stem cells by targeting Notch signaling

ZL Zhao, C Liu, QZ Wang, HW Wu… - Annals of translational …, 2022 - ncbi.nlm.nih.gov
Background Infantile hemangioma (IH) is the most common benign vascular tumor of infancy
and is proposed to arise from hemangioma stem cells (HemSCs). Therapies for IH include …

LncRNA-MCM3AP-AS1 promotes the progression of infantile hemangiomas by increasing miR-138-5p/HIF-1α axis-regulated glycolysis

H Mei, H Xian, J Ke - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Infantile hemangioma (IH) is a common benign tumor of endothelial cells in infants. Most
hemangiomas are self-limited, but a few may develop and lead to serious complications that …

Long noncoding RNA LINC00342 promotes growth of infantile hemangioma by sponging miR-3619-5p from HDGF

Z Liu, Z Kang, Y Dai, H Zheng… - American Journal of …, 2019 - journals.physiology.org
Infantile hemangiomas (IH) are a type of benign vascular neoplasm that may cause
permanent scarring. Hemangioma-derived endothelial cells (HemECs) are commonly used …

MicroRNA‑424 suppresses the proliferation of hemangioma‑derived endothelial cells by targeting VEGFR‑2

Z Fei, M Qiu, X Qi, Y Dai, S Wang… - Molecular …, 2018 - spandidos-publications.com
Hemangioma (HA) is a type of benign tumor common in infancy. The main feature of HA is
the abnormal proliferation of vascular endothelial cells. To date, the pathogenesis of HA …

Silencing microRNA-210 in Hypoxia-Induced HUVEC-Derived Extracellular Vesicles Inhibits Hemangioma

J Ma, X Tao, Y Huang - Cerebrovascular Diseases, 2020 - karger.com
Abstract Background: Hemangioma (Hem) is a benign tumor commonly seen in infancy with
a relative high morbidity. Human umbilical vein endothelial cell (HUVEC)-derived …

LncRNA OIP5-AS1 promotes the proliferation of hemangioma vascular endothelial cells via regulating miR-195-5p/NOB1 axis

J Zhang, T Zhao, L Tian, Y Li - Frontiers in Pharmacology, 2019 - frontiersin.org
Background: Hemangioma, which is a benign vascular neoplasm, has been demonstrated
to be the most common tumor of infancy, resulting from aberrant proliferation of endothelial …

MicroRNA‑195‑5p inhibits the progression of hemangioma via targeting SKI

B Sun, Z Huang, H Yang… - Experimental and …, 2022 - spandidos-publications.com
Hemangioma (HA), which is characterized by aberrant endothelial cell proliferation in blood
vessels, is a common tumor during infancy. MicroRNAs (miRNAs/miRs) collectively …

Exosomal miR-27a-3p derived from tumor-associated macrophage suppresses propranolol sensitivity in infantile hemangioma

C Liu, Z Zhao, S Guo, L Zhang, X Fan, J Zheng - Cellular Immunology, 2021 - Elsevier
Propranolol is the first-line drug for infantile hemangioma (IH) therapy, whereas propranolol
resistance is clinically observed. Tumor-associated macrophages (TAMs)-derived exosomes …