Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing–remitting …
S Rasmussen, Y Wang, P Kivisäkk, RT Bronson… - Brain, 2007 - academic.oup.com
The purpose of this study was to examine the influence of the “good-old-days” bias on
symptom reporting following mild traumatic brain injury (MTBI). The MTBI sample consisted …
symptom reporting following mild traumatic brain injury (MTBI). The MTBI sample consisted …
Longitudinal associations between persistent post-concussion symptoms and blood biomarkers of inflammation and CNS-Injury after mild traumatic brain Injury
GJB Clarke, T Skandsen, H Zetterberg… - Journal of …, 2024 - liebertpub.com
The aim of our study was to investigate the biological underpinnings of persistent post-
concussion symptoms (PPCS) at 3 months following mild traumatic brain injury (mTBI) …
concussion symptoms (PPCS) at 3 months following mild traumatic brain injury (mTBI) …
Systemic inflammation induces axon injury during brain inflammation
B Moreno, JP Jukes, N Vergara‐Irigaray… - Annals of …, 2011 - Wiley Online Library
Objective: Axon injury is a key contributor to the progression of disability in multiple sclerosis
(MS). Systemic infections, which frequently precede relapses in MS, have been linked to …
(MS). Systemic infections, which frequently precede relapses in MS, have been linked to …
Neurochemical aftermath of repetitive mild traumatic brain injury
Importance Evidence is accumulating that repeated mild traumatic brain injury (mTBI)
incidents can lead to persistent, long-term debilitating symptoms and in some cases a …
incidents can lead to persistent, long-term debilitating symptoms and in some cases a …
In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed
ID Vainchtein, J Vinet, N Brouwer, S Brendecke… - Glia, 2014 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous
system (CNS) characterized by loss of myelin accompanied by infiltration of T‐lymphocytes …
system (CNS) characterized by loss of myelin accompanied by infiltration of T‐lymphocytes …
Post-concussion symptom reporting and the “good-old-days” bias following mild traumatic brain injury
The purpose of this study was to examine the influence of the “good-old-days” bias on
symptom reporting following mild traumatic brain injury (MTBI). The MTBI sample consisted …
symptom reporting following mild traumatic brain injury (MTBI). The MTBI sample consisted …
Elevated C-reactive protein levels may be a predictor of persistent unfavourable symptoms in patients with mild traumatic brain injury: a preliminary study
SH Su, W Xu, M Li, L Zhang, YF Wu, F Yu… - Brain, behavior, and …, 2014 - Elsevier
The pathogenesis of persistent unfavourable outcomes following mild traumatic brain injury
(mTBI) are not fully understood. Low-grade systemic inflammation might contribute to the …
(mTBI) are not fully understood. Low-grade systemic inflammation might contribute to the …
Early versus late profiles of inflammatory cytokines after mild traumatic brain injury and their association with neuropsychological outcomes
A Vedantam, J Brennan, HS Levin… - Journal of …, 2021 - liebertpub.com
Despite pre-clinical evidence for the role of inflammation in traumatic brain injury (TBI), there
is limited data on inflammatory biomarkers in mild TBI (mTBI). In this study, we describe the …
is limited data on inflammatory biomarkers in mild TBI (mTBI). In this study, we describe the …
A year-long immune profile of the systemic response in acute stroke survivors
Stroke is a leading cause of cognitive impairment and dementia, but the mechanisms that
underlie post-stroke cognitive decline are not well understood. Stroke produces profound …
underlie post-stroke cognitive decline are not well understood. Stroke produces profound …
Cognitive deficits develop 1 month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge
MM Muccigrosso, J Ford, B Benner, D Moussa… - Brain, behavior, and …, 2016 - Elsevier
Traumatic brain injury (TBI) elicits immediate neuroinflammatory events that contribute to
acute cognitive, motor, and affective disturbance. Despite resolution of these acute …
acute cognitive, motor, and affective disturbance. Despite resolution of these acute …